Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9471296 | 1.00 | NPSR1 (0.42) | NPSR1HCAR2GLO1ALDH1A1CYP2D6 | |
| SCHEMBL11398954 | 0.85 | NPSR1 (0.42) | NPSR1HCAR2GLO1ALDH1A1CYP2D6 | |
| SCHEMBL11290888 | 0.85 | NPSR1 (0.57) | NPSR1HCAR2GLO1ALDH1A1CYP2D6 | |
| SCHEMBL8165735 | 0.84 | NPSR1 (0.45) | NPSR1HCAR2GLO1ALDH1A1CYP2D6 | |
| SCHEMBL8844397 | 0.83 | NPSR1 (0.41) | NPSR1HCAR2GLO1ALDH1A1CYP2D6 | |
| SCHEMBL4795564 | 0.83 | FAAH (0.44) | NPSR1HCAR2GLO1ALDH1A1CYP2D6 | |
| SCHEMBL7640896 | 0.82 | TSHR (0.38) | TSHRKDM4E | |
| SCHEMBL7772532 | 0.82 | NPSR1 (0.47) | NPSR1HCAR2GLO1ALDH1A1CYP2D6 | |
| SCHEMBL703761 | 0.82 | NPSR1 (0.47) | NPSR1HCAR2GLO1ALDH1A1CYP2D6 | |
| SCHEMBL7774727 | 0.82 | NPSR1 (0.47) | NPSR1HCAR2GLO1ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255399-B1 | PROCESS | DAVY McKEE (LONDON) LIMITED (GB) | 1992-03-11 | — | — | EP | claimed |