Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | IDH2 | P48735 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.46 |
| ▸ | IL2 | P60568 | 2/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.45 |
| ▸ | NEK4 | P51957 | 1/20 | 0.45 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.45 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.45 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.45 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629747 | 0.81 | GAA (0.53) | GAAIL2METMEN1KMT2A | |
| SCHEMBL11100265 | 0.81 | HCRTR1 (0.61) | GAAMETMEN1KMT2AHCRTR1 | |
| SCHEMBL30499684 | 0.79 | MAPT (0.62) | GAAMEN1KMT2AKDRNPSR1 | |
| SCHEMBL7607258 | 0.79 | MAPT (0.62) | GAAMEN1KMT2AKDRNPSR1 | |
| SCHEMBL11435335 | 0.79 | RAB9A (0.64) | GAAMEN1KMT2ANPSR1CYP1A2 | |
| SCHEMBL29128686 | 0.79 | KDR (0.50) | GAAIDH2GRM5RIOK2NR3C2 | |
| SCHEMBL352658 | 0.78 | MEN1 (0.54) | GAAIL2MEN1KMT2AALOX15 | |
| SCHEMBL30362400 | 0.78 | TRPV1 (0.57) | GAAGRM5RIOK2MEN1KMT2A | |
| SCHEMBL29608194 | 0.78 | MEN1 (0.54) | GAAIL2MEN1KMT2AALOX15 | |
| SCHEMBL15904287 | 0.77 | TSHR (0.62) | GRM5MEN1KMT2AALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228846-B1 | AMINO-TRIFLUOROMETHYLPYRIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |
| US-4762928-A | PESTICIDES, MEDICINES | ISHIHARA SANGYO KAISHA LTD. (JP) | 1988-08-09 | — | — | US | disclosed |
| EP-0228846-A1 | Amino-trifluoromethylpyridine compound and process for preparing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-07-15 | — | — | EP | disclosed |