Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18698648 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRCYP3A4TP53 | |
| SCHEMBL3455090 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRCYP3A4TP53 | |
| SCHEMBL10442259 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRCYP3A4TP53 | |
| SCHEMBL39398 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRCYP3A4TP53 | |
| SCHEMBL2398240 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRCYP3A4TP53 | |
| SCHEMBL39397 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRCYP3A4TP53 | |
| SCHEMBL12382048 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRCYP3A4TP53 | |
| SCHEMBL9889213 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRCYP3A4TP53 | |
| SCHEMBL14097777 | 0.96 | KDM4E (0.40) | ALDH1A1LMNATSHRCYP3A4TP53 | |
| SCHEMBL18468264 | 0.95 | ALDH1A1 (0.38) | ALDH1A1LMNATSHRCYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0189374-B1 | LIQUID MIXTURES OF 2-(HYDROXY-3-BRANCHED ALKYL-5-METHYLPHENYL)-2H-BENZOTRIAZOLE, PROCESS FOR THEIR PREPARATION AND STABILIZED COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1992-03-18 | — | — | EP | disclosed |
| EP-0189374-A2 | Liquid mixtures of 2-(hydroxy-3-branched alkyl-5-methylphenyl)-2H-benzotriazole, process for their preparation and stabilized compositions containing them | CIBA-GEIGY AG (CH) | 1986-07-30 | — | — | EP | disclosed |