SCHEMBL39398

SCHEMBL39398

CCCCCCCCOC(=O)C(=CC=CN(CC)CC)S(=O)(=O)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.40
▸ LMNA P02545 4/20 0.40
▸ TSHR P16473 3/20 0.40
▸ CYP3A4 P08684 2/20 0.39
▸ TP53 P04637 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ KDM4E B2RXH2 3/20 0.37
▸ POLB P06746 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ PPARG P37231 3/20 0.37
▸ SMN1; SMN2 Q16637 3/20 0.36
▸ RAB9A P51151 2/20 0.36
▸ NPC1 O15118 1/20 0.36
▸ S1PR3 Q99500 1/20 0.36
▸ HCAR2 Q8TDS4 1/20 0.36
▸ KMT2A Q03164 2/20 0.35
▸ ABCB1 P08183 1/20 0.35
▸ MAPT P10636 2/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18698648 1.00 ALDH1A1 (0.40) ALDH1A1LMNATSHRCYP3A4TP53
SCHEMBL3455090 1.00 ALDH1A1 (0.40) ALDH1A1LMNATSHRCYP3A4TP53
SCHEMBL10442259 1.00 ALDH1A1 (0.40) ALDH1A1LMNATSHRCYP3A4TP53
SCHEMBL9629063 1.00 ALDH1A1 (0.40) ALDH1A1LMNATSHRCYP3A4TP53
SCHEMBL2398240 1.00 ALDH1A1 (0.40) ALDH1A1LMNATSHRCYP3A4TP53
SCHEMBL39397 1.00 ALDH1A1 (0.40) ALDH1A1LMNATSHRCYP3A4TP53
SCHEMBL12382048 1.00 ALDH1A1 (0.40) ALDH1A1LMNATSHRCYP3A4TP53
SCHEMBL9889213 1.00 ALDH1A1 (0.40) ALDH1A1LMNATSHRCYP3A4TP53
SCHEMBL14097777 0.96 KDM4E (0.40) ALDH1A1LMNATSHRCYP3A4TP53
SCHEMBL18468264 0.95 ALDH1A1 (0.38) ALDH1A1LMNATSHRCYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 319 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3019143-B1 COMPOSITION COMPRISING A WATER-INSOLUBLE SOLID ORGANIC UV-SCREENING AGENT AND A COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS OREAL (FR) 2019-03-13 — — EP claimed
US-20160151267-A1 COMPOSITION COMPRISING A WATER-INSOLUBLE SOLID ORGANIC UV-SCREENING AGENT AND A COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS L'OREAL (FR) 2016-06-02 — — US claimed
EP-3019143-A1 COMPOSITION COMPRISING A WATER-INSOLUBLE SOLID ORGANIC UV-SCREENING AGENT AND A COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS L'OREAL (FR) 2016-05-18 — — EP claimed
WO-2015003893-A1 COMPOSITION COMPRISING A WATER-INSOLUBLE SOLID ORGANIC UV-SCREENING AGENT AND A COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS L'OREAL (FR) 2015-01-15 — — WO claimed
US-8535647-B2 Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor L'OREAL (FR) 2013-09-17 — — US claimed
EP-2174644-B1 Cosmetic composition comprising a dibenzoylmethane derivative and a dithiolane; Photostabilization of a dibenzoylmethane derivative OREAL (FR) 2012-11-14 — — EP claimed
US-20120269749-A1 COSMETIC COMPOSITIONS COMPRISING AN ESTER DERIVED FROM 4-CARBOXY-2-PYRROLIDINONE AND A MEROCYANIN SCREENING AGENT; USE OF SAID DERIVATIVE AS A SOLVENT FOR A MEROCYANIN SCREENING AGENT L'OREAL (FR) 2012-10-25 — — US claimed
CN-102573995-A Cosmetic compositions comprising an ester derived from 4-carboxy-2-pyrrolidinone and a merocyanin screening agent OREAL 2012-07-11 — — CN claimed
US-8025867-B2 Photoprotective cosmetic compositions comprising photostabilized dibenzoylmethane compounds and merocyanine sulfone compounds L'OREAL (FR) 2011-09-27 — — US claimed
US-20100183529-A1 Cosmetic compositions comprising photostabilized dibenzoylmethane compounds and 2-pyrrolidinone-4- carboxy esters L'OREAL (FR) 2010-07-22 — — US claimed
US-20100172944-A1 COMBINATION OF MONOSACCHARIDES WITH SUNSCREENS AND USE THEREOF L'OREAL (FR) 2010-07-08 — — US claimed
EP-2204165-A1 Combination of monosaccharides with solar filters and cosmetic use thereof L'OREAL (FR) 2010-07-07 — — EP claimed
EP-2193782-A1 Cosmetic composition comprising a dibenzoylmethane derivative and a 2-pyrrolidinone-4-carboxy ester compound; method for the photostabilization of the dibenzoylmethane derivative L'Oreal (FR) 2010-06-09 — — EP claimed
EP-2174644-A1 Cosmetic composition comprising a dibenzoylmethane derivative and a dithiolane; Photostabilization of a dibenzoylmethane derivative L'OREAL (FR) 2010-04-14 — — EP claimed
US-20100086502-A1 Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor L'OREAL (FR) 2010-04-08 — — US claimed
US-20080305058-A1 Photoprotective cosmetic compositions comprising photostabilized dibenzoylmethane compounds and merocyanine sulfone compounds L'OREAL (FR) 2008-12-11 — — US claimed
US-12616647-B2 Non-pulverulent antisun composition comprising a polar oil phase and hydrophobic silica aerogel particles L'OREAL (FR) 2026-05-05 — — US disclosed
US-20260027027-A1 FRAGRANCED COMPOSITION COMPRISING AT LEAST ONE SULFUR-COMPRISING ANTIOXIDANT COMPOUND, AT LEAST ONE ORGANIC UV SCREENING AGENT AND AT LEAST ONE FRAGRANCING SUBSTANCE OREAL (FR) 2026-01-29 — — US disclosed
US-20070104662-A1 Ultraviolet ray absorbing composite powder IWASE COSFA CO., LTD. (JP) 2007-05-10 — — US disclosed
EP-1782792-A1 Ultraviolet ray absorbing composite powder Iwase Cosfa Co., Ltd. (JP) 2007-05-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160151267-A1 COMPOSITION COMPRISING A WATER-INSOLUBLE SOLID ORGANIC UV-SCREENING AGENT AND A COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS F2, F12, C1S ALDH1A1 1323/4885LMNA 1274/4885TSHR 4333/4885
US-20120269749-A1 COSMETIC COMPOSITIONS COMPRISING AN ESTER DERIVED FROM 4-CARBOXY-2-PYRROLIDINONE AND A MEROCYANIN SCREENING AGENT; USE OF SAID DERIVATIVE AS A SOLVENT FOR A MEROCYANIN SCREENING AGENT PYCR1, TYR, PAH ALDH1A1 661/4885LMNA 1104/4885TSHR 4435/4885
US-20260027027-A1 FRAGRANCED COMPOSITION COMPRISING AT LEAST ONE SULFUR-COMPRISING ANTIOXIDANT COMPOUND, AT LEAST ONE ORGANIC UV SCREENING AGENT AND AT LEAST ONE FRAGRANCING SUBSTANCE CBR3, CBR1, ERCC1 ALDH1A1 52/4885LMNA 2021/4885TSHR 4167/4885
US-20100086502-A1 Cosmetic/sunscreen compositions containing dibenzoylmethane compounds and dithiolane compound photostabilizers therefor NOTUM, DDT, FDFT1 ALDH1A1 206/4885LMNA 4021/4885TSHR 3881/4885
US-20070104662-A1 Ultraviolet ray absorbing composite powder XRCC5, XRCC6, ERCC1 ALDH1A1 162/4885LMNA 2155/4885TSHR 2201/4885
US-12616647-B2 Non-pulverulent antisun composition comprising a polar oil phase and hydrophobic silica aerogel particles SMURF1, EBP, SPTLC3 ALDH1A1 3993/4885LMNA 1535/4885TSHR 3450/4885
US-20080305058-A1 Photoprotective cosmetic compositions comprising photostabilized dibenzoylmethane compounds and merocyanine sulfone compounds DDT, DSG1, DSC1 ALDH1A1 809/4885LMNA 1501/4885TSHR 4693/4885
US-20100183529-A1 Cosmetic compositions comprising photostabilized dibenzoylmethane compounds and 2-pyrrolidinone-4- carboxy esters CYP1B1, C1S, DDT ALDH1A1 305/4885LMNA 1653/4885TSHR 3085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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