Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629714 | 0.81 | NOS3 (0.69) | NOS3NOS2KDM4EBACE1HSD11B1 | |
| SCHEMBL2479769 | 0.79 | NOS3 (0.47) | NOS3NOS2KDM4EALDH1A1KMT2A | |
| SCHEMBL183159 | 0.79 | NOS3 (0.46) | NOS3NOS2KDM4EALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL29857654 | 0.78 | NOS3 (0.45) | NOS3NOS2KDM4EALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL28202486 | 0.78 | NOS3 (0.45) | NOS3NOS2KDM4EALDH1A1KMT2A | |
| Formic Acid SCHEMBL31491080 | 0.70 | NAPRT (0.42) | NOS3NOS2KMT2AHSD11B1TRPV1 | |
| Trifluoroacetic Acid SCHEMBL30699729 | 0.69 | NAPRT (0.49) | HSD11B1L3MBTL1TRPV1TLR7HSD17B10 | |
| SCHEMBL1255100 | 0.68 | SLC22A12 (0.43) | NOS3NOS2HSD11B1SLC40A1 | |
| SCHEMBL272886 | 0.68 | NOS3 (0.54) | NOS3NOS2KDM4EALDH1A1BACE1 | |
| SCHEMBL23344931 | 0.68 | NOS3 (0.42) | NOS3NOS2KDM4EBACE1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228846-B1 | AMINO-TRIFLUOROMETHYLPYRIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-04-22 | — | — | EP | claimed |