Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629259 | 0.89 | ABCB11 (0.45) | ABCB11ALDH1A1KDM4ESMN1; SMN2TUBB4A | |
| SCHEMBL9629409 | 0.89 | ABCB11 (0.48) | ABCB11ALDH1A1KDM4ESMN1; SMN2TUBB4A | |
| SCHEMBL9713977 | 0.87 | ABCB11 (0.44) | ABCB11ALDH1A1KDM4ESMN1; SMN2BACE1 | |
| SCHEMBL9642665 | 0.87 | ABCB11 (0.69) | ABCB11ALDH1A1KDM4ESMN1; SMN2TUBB4A | |
| SCHEMBL9629394 | 0.84 | KDM4E (0.56) | ABCB11ALDH1A1KDM4ESMN1; SMN2BACE1 | |
| SCHEMBL9627870 | 0.82 | ABCB11 (0.46) | ABCB11ALDH1A1KDM4ETUBB4ATUBB | |
| SCHEMBL9642480 | 0.78 | ABCB11 (0.57) | ABCB11ALDH1A1KDM4ESMN1; SMN2TUBB4A | |
| SCHEMBL9643550 | 0.78 | ABCB11 (0.57) | ABCB11ALDH1A1KDM4ESMN1; SMN2TUBB4A | |
| SCHEMBL10458777 | 0.77 | ABCB11 (0.51) | ABCB11ALDH1A1KDM4ESMN1; SMN2TUBB4A | |
| SCHEMBL9642621 | 0.77 | ABCB11 (0.48) | ABCB11ALDH1A1KDM4ESMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |