Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629409 | 0.90 | ABCB11 (0.48) | ABCB11NQO1MTNR1ABACE1HPGD | |
| SCHEMBL9657958 | 0.88 | LDHA (0.48) | ABCB11NQO1ALOX5KDM4ETP53 | |
| SCHEMBL9629384 | 0.86 | ABCB11 (0.65) | ABCB11NQO1ALOX5KDM4ETP53 | |
| SCHEMBL9643550 | 0.83 | ABCB11 (0.57) | ABCB11BACE1HPGDKDM4ETP53 | |
| SCHEMBL9629261 | 0.82 | ABCB11 (0.54) | ABCB11BACE1HPGDKDM4EGAA | |
| SCHEMBL9642665 | 0.79 | ABCB11 (0.69) | ABCB11BACE1HPGDKDM4ETP53 | |
| SCHEMBL9642480 | 0.77 | ABCB11 (0.57) | ABCB11BACE1HPGDKDM4EMAPT | |
| SCHEMBL9628241 | 0.77 | KDM4E (0.50) | ABCB11BACE1ALOX5KDM4ETP53 | |
| SCHEMBL9627592 | 0.77 | ABCB11 (0.51) | ABCB11ALOX5HPGDKDM4ETP53 | |
| SCHEMBL9629259 | 0.77 | ABCB11 (0.45) | ABCB11NQO1MTNR1ABACE1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |