Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.70 |
| ▸ | MAOB | P27338 | 1/20 | 0.70 |
| ▸ | CDC25A | P30304 | 2/20 | 0.68 |
| ▸ | CDC25B | P30305 | 2/20 | 0.68 |
| ▸ | ELANE | P08246 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642524 | 0.92 | ELANE (0.67) | MAOAMAOBCDC25ACDC25BELANE | |
| SCHEMBL571353 | 0.83 | MAOA (1.00) | MAOAMAOBCDC25ACDC25BELANE | |
| SCHEMBL30905230 | 0.83 | MAOA (1.00) | MAOAMAOBCDC25ACDC25BELANE | |
| SCHEMBL5811522 | 0.83 | CDC25A (0.66) | MAOAMAOBCDC25ACDC25BALDH1A1 | |
| SCHEMBL9627948 | 0.81 | CDC25A (0.63) | MAOAMAOBCDC25ACDC25BELANE | |
| SCHEMBL3414838 | 0.81 | CDC25B (1.00) | CDC25ACDC25BALDH1A1MAPTPOLB | |
| SCHEMBL30002742 | 0.81 | CDC25B (1.00) | CDC25ACDC25BALDH1A1MAPTPOLB | |
| SCHEMBL9641890 | 0.80 | ELANE (0.52) | MAOAMAOBCDC25ACDC25BELANE | |
| SCHEMBL9627431 | 0.79 | CDC25A (0.65) | MAOAMAOBCDC25ACDC25BELANE | |
| SCHEMBL9629411 | 0.79 | CDC25A (0.65) | MAOAMAOBCDC25ACDC25BELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |