SCHEMBL3414838

SCHEMBL3414838

COC1=C(C)C(=O)c2ccccc2C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 6/20 1.00
CDC25A P30304 5/20 1.00
MAPT P10636 9/20 0.77
ALDH1A1 P00352 8/20 0.77
POLB P06746 7/20 0.77
KDM4E B2RXH2 6/20 0.77
LMNA P02545 5/20 0.77
HPGD P15428 5/20 0.77
SMN1; SMN2 Q16637 5/20 0.77
TDP1 Q9NUW8 4/20 0.77
RAB9A P51151 4/20 0.77
MAP2K7 O14733 3/20 0.77
GMNN O75496 1/20 0.77
TP53 P04637 1/20 0.77
CYP1A2 P05177 1/20 0.77
CYP3A4 P08684 1/20 0.77
CYP2D6 P10635 1/20 0.77
CYP2C9 P11712 1/20 0.77
ALOX15 P16050 1/20 0.77
CYP2C19 P33261 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30002742 1.00 CDC25B (1.00) CDC25BCDC25AMAPTALDH1A1POLB
SCHEMBL14398053 0.91 CDC25B (0.83) CDC25BCDC25AMAPTALDH1A1POLB
SCHEMBL29545010 0.87 MAPT (1.00) CDC25BCDC25AMAPTALDH1A1POLB
SCHEMBL571557 0.87 MAPT (1.00) CDC25BCDC25AMAPTALDH1A1POLB
SCHEMBL571026 0.82 CDC25B (0.68) CDC25BCDC25AMAPTALDH1A1POLB
SCHEMBL29941466 0.82 CDC25B (0.68) CDC25BCDC25AMAPTALDH1A1POLB
SCHEMBL9629285 0.81 MAOA (0.70) CDC25BCDC25AMAPTALDH1A1POLB
SCHEMBL5811522 0.80 CDC25A (0.66) CDC25BCDC25AMAPTALDH1A1POLB
SCHEMBL9629411 0.80 CDC25A (0.65) CDC25BCDC25AMAPTALDH1A1POLB
Water SCHEMBL8664586 0.79 CDC25B (0.65) CDC25BCDC25AMAPTALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0152852-A2 Antimicrobial agent for treating buildings, building materials, textiles, leather, agricultural products and foodstuffs PÜHRINGER, Josef, Dr. (SE) 1985-08-28 EP claimed
CN-110520433-B Phosphorus-containing phenol compound, phosphorus-containing epoxy resin, curable resin composition or epoxy resin composition, and cured product thereof 日铁化学材料株式会社 2023-12-05 CN disclosed
WO-2023204271-A1 ANTI-SARS-COV-2 AGENT AND COMPOUND USE 国立大学法人 鹿児島大学 2023-10-26 WO disclosed
EP-3620459-B9 PHOSPHORUS-CONTAINING PHENOLIC COMPOUND, PHOSPHORUS-CONTAINING EPOXY RESIN, CURABLE RESIN COMPOSITION THEREOF, OR EPOXY RESIN COMPOSITION AND CURED PRODUCT THEREOF NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2023-10-04 EP disclosed
CN-110951048-B Phosphorus-containing hardener, epoxy resin composition, cured product, prepreg, and laminate 日铁化学材料株式会社 2023-09-29 CN disclosed
EP-3620459-B1 PHOSPHORUS-CONTAINING PHENOLIC COMPOUND, PHOSPHORUS-CONTAINING EPOXY RESIN, CURABLE RESIN COMPOSITION THEREOF, OR EPOXY RESIN COMPOSITION AND CURED PRODUCT THEREOF NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2023-05-24 EP disclosed
US-11613509-B2 Radical polymerization control agent and radical polymerization control method KAWASAKI KASEI CHEMICALS LTD. (JP) 2023-03-28 US disclosed
CN-110194843-B Phosphorus-containing phenoxy resin, resin composition, material for circuit board, and cured product 日铁化学材料株式会社 2023-01-03 CN disclosed
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed
US-20210122692-A1 RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD KAWASAKI KASEI CHEMICALS LTD. (JP) 2021-04-29 US disclosed
US-5134161-A Enzyme inhibitors for skin disorders, antiinflammatory agents SYNTEX (U.S.A.) INC. (US) 1992-07-28 US disclosed
US-5091558-A Topical administeration SYNTEX (U.S.A.) INC. (US) 1992-02-25 US disclosed
US-5089657-A Topical antiinflammatory agents SYNTEX (U.S.A.) INC. (US) 1992-02-18 US disclosed
US-4786652-A TOPICAL ADMINISTRATION SYNTEX (U.S.A.) INC. (US) 1988-11-22 US disclosed
EP-0282006-A1 Naphtalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1988-09-14 EP disclosed
EP-0282056-A2 Naphthalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1988-09-14 EP disclosed
EP-0150831-B1 NAPHTHALENE ANTI-PSORIATIC AGENTS SYNTEX (U.S.A.) INC. (US) 1988-08-10 EP disclosed
US-4758587-A Naphthalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1988-07-19 US disclosed
EP-0152852-A2 Antimicrobial agent for treating buildings, building materials, textiles, leather, agricultural products and foodstuffs PÜHRINGER, Josef, Dr. (SE) 1985-08-28 EP disclosed
EP-0150831-A2 Naphthalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1985-08-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11613509-B2 Radical polymerization control agent and radical polymerization control method PPOX, NOX4, CROCC CDC25B 807/4885CDC25A 732/4885MAPT 188/4885
US-20210122692-A1 RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD PPOX, NOX4, CROCC CDC25B 807/4885CDC25A 732/4885MAPT 188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.