Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.49 |
| ▸ | PTPRC | P08575 | 2/20 | 0.49 |
| ▸ | GAPDH | P04406 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | NQO1 | P15559 | 3/20 | 0.35 |
| ▸ | POR | P16435 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714130 | 0.86 | ELANE (0.38) | CDC25BPTPRCGAPDHIDO1CDC25A | |
| SCHEMBL23271788 | 0.84 | CDC25B (0.47) | CDC25BPTPRCGAPDHIDO1CDC25A | |
| SCHEMBL9629332 | 0.81 | CDC25B (0.49) | CDC25BPTPRCGAPDHIDO1CDC25A | |
| SCHEMBL9627491 | 0.81 | CDC25B (0.53) | CDC25BPTPRCGAPDHIDO1CDC25A | |
| SCHEMBL8582314 | 0.79 | IDO1 (0.58) | CDC25BGAPDHIDO1CDC25AMAPT | |
| SCHEMBL30004088 | 0.79 | IDO1 (0.58) | CDC25BGAPDHIDO1CDC25AMAPT | |
| SCHEMBL9713600 | 0.78 | CDC25B (0.53) | CDC25BPTPRCGAPDHIDO1CDC25A | |
| SCHEMBL9628401 | 0.77 | PTPRC (0.51) | CDC25BPTPRCGAPDHIDO1CDC25A | |
| SCHEMBL9627545 | 0.77 | CDC25B (0.51) | CDC25BPTPRCGAPDHIDO1CDC25A | |
| SCHEMBL9629343 | 0.77 | CDC25B (0.51) | CDC25BPTPRCIDO1CDC25ACTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |