Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.53 |
| ▸ | PTPRC | P08575 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252090 | 0.91 | CDC25B (0.50) | CDC25BPTPRCMAPTL3MBTL1GAPDH | |
| SCHEMBL9628193 | 0.91 | CDC25B (0.54) | CDC25BPTPRCMAPTL3MBTL1GAPDH | |
| SCHEMBL11252510 | 0.84 | GAPDH (0.50) | CDC25BPTPRCMAPTL3MBTL1GAPDH | |
| SCHEMBL9627491 | 0.84 | CDC25B (0.53) | CDC25BPTPRCGAPDHIDO1CDC25A | |
| SCHEMBL9627540 | 0.83 | MAPT (0.49) | CDC25BPTPRCMAPTL3MBTL1HSD17B10 | |
| SCHEMBL9627545 | 0.83 | CDC25B (0.51) | CDC25BPTPRCMAPTL3MBTL1GAPDH | |
| SCHEMBL9628401 | 0.83 | PTPRC (0.51) | CDC25BPTPRCGAPDHIDO1CDC25A | |
| SCHEMBL9629343 | 0.83 | CDC25B (0.51) | CDC25BPTPRCIDO1CDC25AGAA | |
| SCHEMBL9627607 | 0.81 | CDC25B (0.50) | CDC25BPTPRCMAPTL3MBTL1GAPDH | |
| SCHEMBL10883121 | 0.81 | MAPT (0.70) | PTPRCMAPTL3MBTL1HSD17B10ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |