Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 2/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | NQO1 | P15559 | 2/20 | 0.33 |
| ▸ | POR | P16435 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629429 | 0.86 | CDC25B (0.49) | GAPDHCDC25BPTPRCIDO1CDC25A | |
| SCHEMBL11106678 | 0.83 | GAPDH (0.57) | ELANEGAPDHCDC25BPTPRCIDO1 | |
| SCHEMBL9713511 | 0.78 | S100A4 (0.41) | GAPDHCDC25BPTPRCIDO1CDC25A | |
| SCHEMBL9628358 | 0.78 | CDC25B (0.61) | GAPDHCDC25BPTPRCIDO1CDC25A | |
| SCHEMBL8582314 | 0.77 | IDO1 (0.58) | GAPDHCDC25BIDO1CDC25AMAPT | |
| SCHEMBL30004088 | 0.77 | IDO1 (0.58) | GAPDHCDC25BIDO1CDC25AMAPT | |
| SCHEMBL9714028 | 0.74 | CDC25B (0.42) | GAPDHCDC25BPTPRCIDO1CDC25A | |
| SCHEMBL11252366 | 0.73 | PTPRC (0.38) | CDC25BPTPRCMAPTPTPN1MEN1 | |
| SCHEMBL28724662 | 0.73 | GAPDH (0.53) | GAPDHCDC25BPTPRCIDO1CDC25A | |
| SCHEMBL23271788 | 0.71 | CDC25B (0.47) | GAPDHCDC25BPTPRCIDO1CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |