Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658121 | 0.92 | HTT (0.52) | HTTPTGS2 | |
| SCHEMBL9628323 | 0.91 | HTT (0.54) | HTTALOX5 | |
| SCHEMBL9627803 | 0.90 | ALOX5 (0.52) | HTTALOX5 | |
| SCHEMBL9627400 | 0.87 | HTT (0.56) | HTTALOX5PTGS2 | |
| SCHEMBL9628087 | 0.87 | HTT (0.56) | HTTALOX5PTGS2 | |
| SCHEMBL9628363 | 0.87 | HTT (0.55) | HTTPTGS2 | |
| SCHEMBL9627747 | 0.86 | HTT (0.57) | HTTALOX5PTGS2 | |
| SCHEMBL9628345 | 0.85 | HTT (0.56) | HTTALOX5 | |
| SCHEMBL19612401 | 0.85 | SLC2A1 (0.45) | HTT | |
| SCHEMBL9660327 | 0.83 | HTT (0.50) | HTTALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |