Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2689971 | 0.89 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL2988368 | 0.89 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL2982658 | 0.89 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL9628763 | 0.87 | ALDH1A1 (0.48) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL4740185 | 0.83 | LMNA (0.68) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL22248495 | 0.83 | LMNA (0.57) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL11386694 | 0.83 | LMNA (0.57) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL9011176 | 0.83 | MAPT (0.58) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL2700361 | 0.83 | LMNA (0.68) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL880135 | 0.83 | LMNA (0.57) | LMNAMAPTMAPK1ALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260910-B1 | 3,6-DIPHENYLPYRIDAZINES | Chisso Corporation (JP) | 1992-05-27 | — | — | EP | claimed |
| EP-0260910-B1 | 3,6-DIPHENYLPYRIDAZINES | Chisso Corporation (JP) | 1992-05-27 | — | — | EP | disclosed |
| US-4818430-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1989-04-04 | — | — | US | disclosed |
| EP-0260910-A1 | 3,6-Diphenylpyridazines | Chisso Corporation (JP) | 1988-03-23 | — | — | EP | disclosed |