Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ADH1B | P00325 | 1/20 | 0.42 |
| ▸ | ADH1C | P00326 | 1/20 | 0.42 |
| ▸ | ADH1A | P07327 | 1/20 | 0.42 |
| ▸ | ADH7 | P40394 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23023141 | 0.85 | EPHX1 (0.55) | MEN1KMT2ATDP1MAOADPP7 | |
| SCHEMBL14217534 | 0.80 | MEN1 (0.44) | MEN1KMT2ATDP1MAOADPP7 | |
| SCHEMBL1654 | 0.79 | MEN1 (0.78) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL5799878 | 0.79 | MEN1 (0.78) | MEN1KMT2ATDP1MAOACHRM2 | |
| Benzene SCHEMBL11697595 | 0.79 | MEN1 (0.78) | MEN1KMT2ATDP1MAOACHRM2 | |
| Bromide SCHEMBL998627 | 0.77 | MEN1 (0.74) | MEN1KMT2ATDP1MAOACHRM2 | |
| Ammonia Solution, Strong SCHEMBL2064651 | 0.77 | MEN1 (0.74) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL3990993 | 0.77 | MEN1 (0.74) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL21550054 | 0.77 | MEN1 (0.74) | MEN1KMT2ATDP1MAOACHRM2 | |
| Hydrochloric Acid SCHEMBL1862144 | 0.77 | MEN1 (0.74) | MEN1KMT2ATDP1MAOACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213080-B1 | HYDROGENATED PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-05-20 | — | — | EP | disclosed |
| US-4939160-A | Nootropic agents | CIBA-GEIGY CORPORATION (US) | 1990-07-03 | — | — | US | disclosed |
| US-4833169-A | MEMORY ACTIVATORS | CIBA-GEIGY CORPORATION (US) | 1989-05-23 | — | — | US | disclosed |
| EP-0213080-A2 | Hydrogenated pyridine derivatives | CIBA-GEIGY AG (CH) | 1987-03-04 | — | — | EP | disclosed |