Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629602 | 0.81 | KMT2A (0.53) | KMT2AEPHX2ALDH1A1TP53LMNA | |
| SCHEMBL9628788 | 0.77 | ALDH1A1 (0.62) | KMT2AALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9629579 | 0.75 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL5638460 | 0.74 | KMT2A (0.62) | KMT2AEPHX2TP53LMNAHDAC1 | |
| SCHEMBL5636666 | 0.73 | ALDH1A1 (0.42) | KMT2AEPHX2ALDH1A1TP53CTSL | |
| SCHEMBL11339018 | 0.71 | ALDH1A1 (0.38) | KMT2AEPHX2ALDH1A1CTSLMAPT | |
| SCHEMBL10226479 | 0.69 | GAA (0.53) | KMT2AEPHX2ALDH1A1TP53CTSL | |
| SCHEMBL13776033 | 0.67 | ALDH1A1 (0.38) | KMT2AEPHX2ALDH1A1CTSLLMNA | |
| SCHEMBL434490 | 0.67 | EPHX2 (0.77) | KMT2AEPHX2ALDH1A1LMNAMMP12 | |
| SCHEMBL10226490 | 0.67 | EPHX2 (0.49) | KMT2AEPHX2ALDH1A1LMNAMMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340581-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4925994-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| EP-0340581-A2 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |