Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5638460 | 0.90 | KMT2A (0.62) | KMT2AEPHX2TP53HDAC1HDAC8 | |
| SCHEMBL9628745 | 0.82 | KMT2A (0.46) | KMT2AEPHX2TP53HDAC1HDAC8 | |
| SCHEMBL9629595 | 0.81 | HDAC1 (0.48) | KMT2ATP53HDAC1HDAC8HDAC6 | |
| SCHEMBL9629681 | 0.81 | KMT2A (0.49) | KMT2ATP53HDAC1HDAC8HDAC6 | |
| SCHEMBL9629614 | 0.81 | KMT2A (0.39) | KMT2AEPHX2TP53HDAC1HDAC8 | |
| SCHEMBL9628766 | 0.81 | MAOA (0.55) | KMT2ATP53HDAC1HDAC8HDAC6 | |
| SCHEMBL434490 | 0.80 | EPHX2 (0.77) | KMT2AEPHX2LMNARAB9AMMP12 | |
| SCHEMBL8853748 | 0.79 | EPHX2 (0.70) | KMT2AEPHX2TP53HDAC1HDAC8 | |
| SCHEMBL9629024 | 0.78 | KIF11 (0.47) | HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL9628996 | 0.77 | MAPT (0.53) | KMT2AEPHX2TP53HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340581-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4925994-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| EP-0340581-A2 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |