SCHEMBL962962

SCHEMBL962962

C=COC(=O)C1CC2C=CC1C2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.49
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 9/20 0.40
KMT2A Q03164 3/20 0.39
RAB9A P51151 1/20 0.39
POLB P06746 2/20 0.38
HSD17B10 Q99714 2/20 0.38
APEX1 P27695 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
ESR2 Q92731 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HPGD P15428 1/20 0.38
THRB P10828 1/20 0.33
MAPK1 P28482 2/20 0.32
EPHX2 P34913 2/20 0.32
MAPT P10636 1/20 0.32
MEN1 O00255 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10036791 0.84 LMNA (0.50) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL2775560 0.79 LMNA (0.53) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL14216898 0.79 KDM4E (0.46) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL2201028 0.79 LMNA (0.57) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL2776167 0.79 LMNA (0.57) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL14378676 0.79 LMNA (0.57) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL5068281 0.78 ALDH1A1 (0.45) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL16001621 0.76 LMNA (0.50) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL19506921 0.76 ALDH1A1 (0.32) ALDH1A1
SCHEMBL18107694 0.76 KDM4E (0.42) LMNAKDM4EALDH1A1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023189302-A1 RESIN COMPOSITION, MOLDED ARTICLE, AND OPTICAL MEMBER 日本ゼオン株式会社 2023-10-05 WO disclosed
EP-2248839-B1 CRYSTALLINE NORBORNENE RING-OPENING POLYMER HYDRIDE AND MOLDED ARTICLE OF SAME ZEON CORP (JP) 2018-03-28 EP disclosed
EP-1655321-B1 POLYMERIZABLE COMPOSITIONS AND MOLDED ARTICLES PRODUCED BY USING THE SAME ZEON CORP (JP) 2012-11-21 EP disclosed
US-8053531-B2 Hydrogenated crystalline norbornene ring-opening polymer and molded article ZEON CORPORATION (JP) 2011-11-08 US disclosed
US-20110021731-A1 HYDROGENATED CRYSTALLINE NORBORNENE RING-OPENING POLYMER AND MOLDED ARTICLE ZEON CORPORATION (JP) 2011-01-27 US disclosed
EP-2248839-A1 CRYSTALLINE NORBORNENE RING-OPENING POLYMER HYDRIDE AND MOLDED ARTICLE OF SAME Zeon Corporation (JP) 2010-11-10 EP disclosed
US-7381782-B2 Polymerizable composition and molded articles produced by using the same ZEON CORPORATION (JP) 2008-06-03 US disclosed
US-20060258828-A1 Polymerizable composition and molded articles produced by using the same ZEON CORPORATION (JP) 2006-11-16 US disclosed
EP-1655321-A1 POLYMERIZABLE COMPOSITIONS AND MOLDED ARTICLES PRODUCED BY USING THE SAME Zeon Corporation (JP) 2006-05-10 EP disclosed
US-5408005-A Emulsion/suspension/bulk and graft copolymerization; phase transfer agent to neutralize charge of anionic surfactant; crosslinking NORSOLOR (FR) 1995-04-18 US disclosed
US-5115031-A Addition polymerization in the presence of nonionic surfactant by emulsion polymerization, grafting monomers for impact strength NORSOLOR (FR) 1992-05-19 US disclosed
US-4952635-A PREPARING A LATEX, GRAFTING ACRYLIC MONOMERS OR POLYMERS ONTO RUBBER; TRANSFERRING LATEX ONTO ACRYLIC POLYMER; NONIONIC SURFACTANT INTERPOLYMERIC COMPLEXING NORSOLOR (FR) 1990-08-28 US disclosed
US-4927867-A MODIFIED WITH AN ELASTOMERIC LATEX NORSOLOR (FR) 1990-05-22 US disclosed
US-4897449-A POLYMERS/SHELL-CORE/ NORSOLOR (FR) 1990-01-30 US disclosed
US-4617329-A POLYESTER OR POLYCARBONATE AND MULTISTAGE STYRENIC POLYMER ROHM AND HAAS COMPANY (US) 1986-10-14 US disclosed