SCHEMBL9629642

SCHEMBL9629642

COc1ccc(Nc2ccc(C)cc2C)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.65
FFAR4 Q5NUL3 1/20 0.56
MAPK1 P28482 3/20 0.55
MAPT P10636 3/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
KDM4E B2RXH2 2/20 0.55
THRB P10828 2/20 0.55
RECQL P46063 2/20 0.55
RAB9A P51151 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
NPC1 O15118 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
GALR2 O43603 1/20 0.54
RAPGEF4 Q8WZA2 1/20 0.52
ALDH1A1 P00352 4/20 0.51
AKR1C3 P42330 2/20 0.51
AKR1C2 P52895 2/20 0.51
LMNA P02545 3/20 0.49
NCOA1 Q15788 1/20 0.49
NCOA3 Q9Y6Q9 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6999192 0.89 GAA (0.75) GAAFFAR4MAPK1MAPTL3MBTL1
SCHEMBL25634740 0.89 GAA (0.80) GAAMAPK1MAPTL3MBTL1KDM4E
SCHEMBL29445703 0.87 RAPGEF4 (0.65) GAAMAPK1MAPTL3MBTL1RAB9A
SCHEMBL1921159 0.87 RAPGEF4 (0.65) GAAMAPK1MAPTL3MBTL1RAB9A
SCHEMBL3634234 0.86 GAA (0.55) GAAMAPK1MAPTL3MBTL1KDM4E
SCHEMBL21369667 0.86 GAA (0.56) GAAFFAR4MAPK1MAPTL3MBTL1
SCHEMBL4230288 0.85 GAA (0.64) GAAFFAR4MAPK1MAPTL3MBTL1
SCHEMBL30146931 0.85 RAPGEF4 (0.63) GAAMAPTL3MBTL1KDM4ERECQL
SCHEMBL5667044 0.85 RAPGEF4 (0.63) GAAMAPTL3MBTL1KDM4ERECQL
SCHEMBL186343 0.83 NR4A1 (0.62) GAAMAPK1MAPTL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4186708-A1 ON-MACHINE-DEVELOPING-TYPE PLANOGRAPHIC PRINTING PLATE ORIGINAL PLATE, METHOD FOR MANUFACTURING PLANOGRAPHIC PRINTING PLATE, AND PLANOGRAPHIC PRINTING METHOD FUJIFILM Corporation (JP) 2023-05-31 EP disclosed
US-5166350-A Process for the manufacture of fluoran compounds CIBA-GEIGY CORPORATION (US) 1992-11-24 US disclosed