Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.68 |
| ▸ | MAOA | P21397 | 4/20 | 0.68 |
| ▸ | SNCA | P37840 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.49 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RYR2 | Q92736 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853682 | 0.91 | MAOB (0.72) | MAOBMAOASNCAHTTKDM4E | |
| SCHEMBL9628766 | 0.90 | MAOA (0.55) | MAOBMAOASNCAHTTKDM4E | |
| SCHEMBL15631693 | 0.81 | MAOB (1.00) | MAOBMAOASNCAHTTPDE3B | |
| SCHEMBL8853694 | 0.81 | MAOA (0.57) | MAOBMAOASNCAHTTKDM4E | |
| SCHEMBL28978962 | 0.77 | PDE3B (0.56) | MAOBMAOAPDE3BPDE3ALMNA | |
| SCHEMBL3186685 | 0.77 | PDE3B (0.56) | MAOBMAOAPDE3BPDE3ALMNA | |
| SCHEMBL6366190 | 0.76 | KDM4E (0.82) | MAOBMAOAHTTKDM4EPDE3B | |
| SCHEMBL8853746 | 0.75 | MAOB (0.59) | MAOBMAOAHTTKDM4EPDE3B | |
| SCHEMBL30423867 | 0.75 | RYR2 (0.50) | MAOBMAOASNCAHTTKDM4E | |
| SCHEMBL9628996 | 0.74 | MAPT (0.53) | MAOBMAOASNCANOX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340581-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4925994-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| EP-0340581-A2 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |