Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1756087 | 0.89 | HDAC1 (0.51) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| SCHEMBL9628788 | 0.79 | ALDH1A1 (0.62) | MAPTNPC1BRD4CREBBPALDH1A1 | |
| SCHEMBL13323 | 0.77 | ALDH1A1 (0.60) | MAPTBRD4CREBBPALDH1A1GAA | |
| SCHEMBL9629681 | 0.77 | KMT2A (0.49) | MAPTMAPK13GAAMEN1KMT2A | |
| SCHEMBL9629602 | 0.77 | KMT2A (0.53) | NPC1BRD4CREBBPALDH1A1GAA | |
| SCHEMBL9629595 | 0.77 | HDAC1 (0.48) | MAPTNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL6632266 | 0.77 | HDAC1 (0.42) | MAPTNPC1MAPK13MAPK12MAPK11 | |
| Hydrochloric Acid SCHEMBL30648399 | 0.76 | ALDH1A1 (0.58) | MAPTBRD4CREBBPALDH1A1GAA | |
| SCHEMBL9629644 | 0.74 | MAOB (0.68) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9628745 | 0.74 | KMT2A (0.46) | MAPTALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1313443-A | — | — | None | — | — | JP | disclosed |
| EP-0340581-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4925994-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| JP-H01313443-A | METHOD FOR RING CHLORINATION OF AROMATIC HYDROCARBON | BAYER AG | 1989-12-18 | — | — | JP | disclosed |
| EP-0340581-A2 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |