Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608757 | 0.86 | CYP1A2 (0.55) | GAAHTTALDH1A1MAPTNPC1 | |
| SCHEMBL5451204 | 0.83 | MAPT (0.58) | GAAHTTALDH1A1MAPTPOLB | |
| SCHEMBL1921827 | 0.83 | RAPGEF4 (0.61) | GAAHTTALDH1A1MAPTPOLB | |
| SCHEMBL21241199 | 0.81 | RAPGEF4 (0.59) | GAAHTTALDH1A1MAPTPOLB | |
| SCHEMBL3191755 | 0.81 | MAPT (0.69) | GAAHTTALDH1A1MAPTPOLB | |
| SCHEMBL5923798 | 0.79 | MAPT (0.67) | GAAHTTALDH1A1MAPTPOLB | |
| SCHEMBL29196035 | 0.79 | RAPGEF4 (0.71) | GAAHTTALDH1A1MAPTNPC1 | |
| SCHEMBL18734560 | 0.77 | MAPK1 (0.61) | GAAHTTALDH1A1MAPTPOLB | |
| SCHEMBL10480096 | 0.77 | MAPT (0.71) | GAAHTTALDH1A1MAPTPOLB | |
| SCHEMBL11219348 | 0.76 | MAPT (0.60) | GAAHTTALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166350-A | Process for the manufacture of fluoran compounds | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |