Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241199 | 0.93 | RAPGEF4 (0.59) | RAPGEF4MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL29196035 | 0.91 | RAPGEF4 (0.71) | RAPGEF4MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL9629646 | 0.83 | GAA (0.59) | RAPGEF4MEN1KMT2AGAARAB9A | |
| SCHEMBL8691617 | 0.83 | RAPGEF4 (0.57) | RAPGEF4MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL1921160 | 0.82 | RAPGEF4 (0.63) | RAPGEF4MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL17858100 | 0.82 | RAPGEF4 (0.61) | RAPGEF4MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL28360150 | 0.82 | CYP2C9 (0.49) | RAPGEF4MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL30575353 | 0.80 | RAPGEF4 (0.61) | RAPGEF4MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL8598906 | 0.80 | RAPGEF4 (0.61) | RAPGEF4MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL1921826 | 0.79 | RAPGEF4 (0.63) | RAPGEF4MEN1KMT2AGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139977-B1 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | EXXONMOBIL RES & ENG CO (US) | 2012-09-05 | — | — | EP | claimed |
| US-7759295-B2 | Lubricating compositions containing ashless catalytic antioxidant additives | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2010-07-20 | — | — | US | claimed |
| EP-2139977-A2 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | ExxonMobil Research and Engineering Company (US) | 2010-01-06 | — | — | EP | claimed |
| WO-2008123940-A2 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2008-10-16 | — | — | WO | claimed |
| US-20080248985-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2008-10-09 | — | — | US | claimed |
| EP-1528074-B1 | NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | TOSOH CORP (JP) | 2014-03-26 | — | — | EP | disclosed |
| EP-2139977-B1 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | EXXONMOBIL RES & ENG CO (US) | 2012-09-05 | — | — | EP | disclosed |
| EP-2139977-B1 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | EXXONMOBIL RES & ENG CO (US) | 2012-09-05 | — | — | EP | disclosed |
| EP-2327739-A1 | Novel triarylamine polymer, process for its production and its use | TOSOH CORPORATION (JP) | 2011-06-01 | — | — | EP | disclosed |
| US-20100217043-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | PATIL ABHIMANYU O | 2010-08-26 | — | — | US | disclosed |
| US-20100217043-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | PATIL ABHIMANYU O | 2010-08-26 | — | — | US | disclosed |
| US-20100217043-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | PATIL ABHIMANYU O | 2010-08-26 | — | — | US | disclosed |
| US-20080248985-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2008-10-09 | — | — | US | disclosed |
| US-20080248985-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2008-10-09 | — | — | US | disclosed |
| US-20080248985-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2008-10-09 | — | — | US | disclosed |
| US-20060241278-A1 | Novel triarylamine polymer, process for producing the same, and use thereof | TOSOH CORPORATION (JP) | 2006-10-26 | — | — | US | disclosed |
| US-20060017040-A9 | Novel triarylamine polymer, process for producing the same, and use thereof | SUZUKI TAKAO | 2006-01-26 | — | — | US | disclosed |
| EP-1528074-A1 | NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Tosoh Corporation (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-20040262574-A1 | Novel triarylamine polymer, process for producing the same, and use thereof | TOSOH CORPORATION (JP) | 2004-12-30 | — | — | US | disclosed |
| US-6034206-A | POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE | TOSOH CORPORATION (JP) | 2000-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100217043-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | SOD1, GPX4, GPX1 | RAPGEF4 4464/4885MEN1 4136/4885KMT2A 2303/4885 |
| US-20080248985-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | SOD1, GPX4, GPX1 | RAPGEF4 4464/4885MEN1 4136/4885KMT2A 2303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.