Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629038 | 0.87 | ALDH1A1 (0.52) | TSHRTP53ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9629921 | 0.82 | TSHR (0.47) | TSHRTP53ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL11659032 | 0.81 | CYP3A4 (0.42) | TSHRTP53ITGB2ICAM1ITGAL | |
| SCHEMBL3164872 | 0.79 | TP53 (0.48) | TSHRTP53ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL9808917 | 0.75 | HTR2B (0.41) | TSHRTP53ITGB2ICAM1ITGAL | |
| SCHEMBL30142219 | 0.72 | CYP3A4 (0.48) | TSHRITGB2ICAM1ITGALALDH1A1 | |
| SCHEMBL9935155 | 0.72 | CYP3A4 (0.48) | TSHRTP53ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL6815115 | 0.72 | CYP3A4 (0.48) | TSHRITGB2ICAM1ITGALALDH1A1 | |
| SCHEMBL7860592 | 0.71 | CYP3A4 (0.47) | TSHRITGB2ICAM1ITGALALDH1A1 | |
| SCHEMBL2788773 | 0.68 | CYP3A4 (0.43) | TSHRITGB2ICAM1ITGALALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215312-B1 | METHOD FOR PRODUCING OF POLYARYLENE SULFIDES | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1992-03-25 | — | — | EP | disclosed |
| US-4810773-A | HIGH MOLECULAR WEIGHT ENGINEERING THERMOPLASTICS | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1989-03-07 | — | — | US | disclosed |
| EP-0296250-A1 | POLYARYLENE SULFIDE AND PROCESS FOR ITS PRODUCTION | IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) | 1988-12-28 | — | — | EP | disclosed |
| EP-0215312-A1 | Method for producing of polyarylene sulfides | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |