Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808965 | 0.81 | PLA2G7 (0.49) | TSHRCYP3A4TP53PLA2G7ALDH1A1 | |
| SCHEMBL29010805 | 0.77 | TSHR (0.50) | HTR2BPDE4DTSHRCYP3A4TP53 | |
| SCHEMBL2807338 | 0.75 | CYP3A4 (0.65) | HTR2BPDE4DTSHRCYP3A4TP53 | |
| SCHEMBL10452388 | 0.75 | HSD17B10 (0.49) | TSHRCYP3A4TP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL9629797 | 0.75 | TSHR (0.44) | HTR2BPDE4DTSHRCYP3A4TP53 | |
| SCHEMBL14744510 | 0.74 | PLA2G7 (0.66) | HTR2BPDE4DTSHRCYP3A4TP53 | |
| SCHEMBL440944 | 0.71 | TP53 (0.61) | HTR2BPDE4DTSHRCYP3A4TP53 | |
| SCHEMBL29364307 | 0.71 | TP53 (0.61) | HTR2BPDE4DTSHRCYP3A4TP53 | |
| SCHEMBL9629038 | 0.70 | ALDH1A1 (0.52) | TSHRCYP3A4TP53ALDH1A1IDO1 | |
| SCHEMBL9808963 | 0.70 | TSHR (0.48) | HTR2BPDE4DTSHRCYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985463-A | Aminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-01-15 | — | — | US | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |