Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630135 | 1.00 | TLR4 (0.34) | TLR4MAPTCYP2C9ALDH1A1LMNA | |
| SCHEMBL10039503 | 0.84 | TLR4 (0.33) | TLR4 | |
| SCHEMBL9630077 | 0.80 | TLR4 (0.33) | TLR4 | |
| SCHEMBL8905453 | 0.80 | TLR4 (0.33) | TLR4 | |
| SCHEMBL9349806 | 0.80 | SLC6A2 (0.34) | TLR4CYP2C9 | |
| SCHEMBL9630138 | 0.80 | TLR4 (0.36) | TLR4MAPTCYP2C9ALDH1A1LMNA | |
| SCHEMBL9630143 | 0.80 | TLR4 (0.36) | TLR4MAPTCYP2C9ALDH1A1LMNA | |
| SCHEMBL8435370 | 0.80 | SLC6A2 (0.34) | TLR4CYP2C9 | |
| SCHEMBL9347569 | 0.79 | MAPT (0.41) | MAPTCYP2C9 | |
| SCHEMBL9630075 | 0.79 | TRPV4 (0.31) | TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316715-B1 | CYCLOHEXANE DERIVATIVES | Chisso Corporation (JP) | 1992-06-03 | — | — | EP | disclosed |
| US-4853152-A | Cyclohexane derivative | CHISSO CORPORATION (JP) | 1989-08-01 | — | — | US | disclosed |
| EP-0316715-A2 | Cyclohexane derivatives | Chisso Corporation (JP) | 1989-05-24 | — | — | EP | disclosed |