Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630077 | 1.00 | TLR4 (0.33) | TLR4CHRM3 | |
| SCHEMBL10039503 | 0.87 | TLR4 (0.33) | TLR4 | |
| SCHEMBL8433409 | 0.85 | SLC6A3 (0.35) | TLR4 | |
| SCHEMBL8435370 | 0.82 | SLC6A2 (0.34) | TLR4CHRM3 | |
| SCHEMBL9349806 | 0.82 | SLC6A2 (0.34) | TLR4CHRM3 | |
| SCHEMBL9630075 | 0.81 | TRPV4 (0.31) | TLR4 | |
| SCHEMBL9630087 | 0.81 | TRPV4 (0.31) | TLR4 | |
| SCHEMBL9630152 | 0.80 | TLR4 (0.34) | TLR4 | |
| SCHEMBL9630135 | 0.80 | TLR4 (0.34) | TLR4 | |
| SCHEMBL7913831 | 0.79 | GAA (0.36) | TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641429-A | STABLE COMPOUNDS HAVING LOW VISCOSITY AND HIGH DIELECTRIC ANISOTROPY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-06-24 | — | — | US | disclosed |
| EP-0441932-B1 | FLUOROBENZOLE DERIVATIVES AND MESOMORPHOUS MEDIUM | MERCK PATENT GMBH (DE) | 1995-03-15 | — | — | EP | disclosed |
| EP-0628532-A1 | Fluorobenzole derivatives and mesomorphous medium | MERCK PATENT GmbH (DE) | 1994-12-14 | — | — | EP | disclosed |
| EP-0316715-B1 | CYCLOHEXANE DERIVATIVES | Chisso Corporation (JP) | 1992-06-03 | — | — | EP | disclosed |
| WO-1991003450-A1 | FLUOROBENZOLE DERIVATIVES AND MESOMORPHOUS MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-03-21 | — | — | WO | disclosed |
| US-4853152-A | Cyclohexane derivative | CHISSO CORPORATION (JP) | 1989-08-01 | — | — | US | disclosed |
| EP-0316715-A2 | Cyclohexane derivatives | Chisso Corporation (JP) | 1989-05-24 | — | — | EP | disclosed |