Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL504801 | 0.73 | MAPT (0.49) | ALDH1A1SIGMAR1MAPT | |
| Benzene SCHEMBL6698503 | 0.70 | CES1 (0.64) | POLBALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1331954 | 0.70 | CES1 (0.64) | POLBALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL43943 | 0.70 | CES1 (0.64) | POLBALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9688483 | 0.70 | CES1 (0.64) | POLBALDH1A1LMNAMEN1KMT2A | |
| Benzene SCHEMBL11066939 | 0.70 | CES1 (0.64) | POLBALDH1A1LMNAMEN1KMT2A | |
| Benzene SCHEMBL3421936 | 0.70 | CES1 (0.64) | POLBALDH1A1LMNAMEN1KMT2A | |
| Benzene SCHEMBL2333780 | 0.70 | CES1 (0.64) | POLBALDH1A1LMNAMEN1KMT2A | |
| Benzene SCHEMBL7058395 | 0.70 | CES1 (0.64) | POLBALDH1A1LMNAMEN1KMT2A | |
| Benzene SCHEMBL10503945 | 0.70 | CES1 (0.64) | POLBALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153210-A | Hypoglycemic agent, animal growth regulator; veterinary medicine | BEECHAM GROUP P.L.C. (GB) | 1992-10-06 | — | — | US | disclosed |
| EP-0236624-A2 | Substituted phenyl ethanol amines, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-09-16 | — | — | EP | disclosed |