Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 16/20 | 0.79 |
| ▸ | BCHE | P06276 | 10/20 | 0.73 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358434 | 0.86 | ACHE (0.80) | ACHEBCHEPRMT6 | |
| SCHEMBL10697112 | 0.83 | ACHE (0.81) | ACHEBCHEPRMT6 | |
| Ammonia Solution, Strong SCHEMBL9513227 | 0.81 | ACHE (0.79) | ACHEBCHEPRMT6 | |
| SCHEMBL11198862 | 0.81 | ACHE (0.71) | ACHEBCHEPRMT6 | |
| SCHEMBL10358390 | 0.80 | ACHE (0.96) | ACHEBCHEPRMT6 | |
| SCHEMBL10358445 | 0.80 | ACHE (0.83) | ACHEBCHEPRMT6 | |
| SCHEMBL2458150 | 0.79 | ACHE (0.74) | ACHEBCHEPRMT6 | |
| SCHEMBL7995056 | 0.79 | PRMT6 (1.00) | ACHEBCHEPRMT6 | |
| SCHEMBL10358388 | 0.79 | ACHE (0.86) | ACHEBCHEPRMT6 | |
| SCHEMBL10910254 | 0.79 | ACHE (0.80) | ACHEBCHEPRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112995-A | PREPARATION OF SUBSTITUTED ETHENES | GLAXO GROUP LIMITED (GB) | 1992-05-12 | — | — | US | claimed |
| EP-0159012-B1 | SULFONAMIDINES, A PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FERRER INTERNACIONAL, S.A. (ES) | 1989-02-01 | — | — | EP | claimed |
| US-4728655-A | ANTIULCER, H2-ANTAGONISTS | FERRER INTERNACIONAL S.A. (ES) | 1988-03-01 | — | — | US | claimed |
| US-4600780-A | ANTIULCER AGENTS | FERRER INTERNATIONAL, S.A. (ES) | 1986-07-15 | — | — | US | claimed |
| US-4571398-A | Cytosine derivatives having histamine H2 -antagonist activity | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-02-18 | — | — | US | claimed |
| EP-0140466-A2 | Pyrimidinone derivatives, process for their preparation, and their pharmaceutical use | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-05-08 | — | — | EP | claimed |
| EP-0123920-A1 | N-cyano-formamidine compounds, process for preparing them and pharmaceutical compositions containing them | FERRER INTERNACIONAL, S.A. (ES) | 1984-11-07 | — | — | EP | claimed |
| US-5112995-A | PREPARATION OF SUBSTITUTED ETHENES | GLAXO GROUP LIMITED (GB) | 1992-05-12 | — | — | US | disclosed |
| EP-0159012-B1 | SULFONAMIDINES, A PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FERRER INTERNACIONAL, S.A. (ES) | 1989-02-01 | — | — | EP | disclosed |
| US-4738983-A | Ethylenediamine and guanidine-derivatives | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1988-04-19 | — | — | US | disclosed |
| US-4738983-A | Ethylenediamine and guanidine-derivatives | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1988-04-19 | — | — | US | disclosed |
| US-4728655-A | ANTIULCER, H2-ANTAGONISTS | FERRER INTERNACIONAL S.A. (ES) | 1988-03-01 | — | — | US | disclosed |
| US-4728655-A | ANTIULCER, H2-ANTAGONISTS | FERRER INTERNACIONAL S.A. (ES) | 1988-03-01 | — | — | US | disclosed |
| EP-0101379-A1 | Benzamides, their salts, process for their preparation and pharmaceutical compositions containing them | SANOFI S.A. (FR) | 1984-02-22 | — | — | EP | disclosed |
| US-4375435-A | 3-,4-Dihydroimidazo (3,4-c)-1,3-pyrimidines and 4,5-dihydroimidazo (3,4-c)-1,3-diazepines | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-03-01 | — | — | US | disclosed |
| EP-0069664-A1 | Aminobenzamides, their salts, process for their preparation and pharmaceutical compositions containing them | SANOFI S.A. (FR) | 1983-01-12 | — | — | EP | disclosed |
| EP-0057227-A1 | IMINO-ALKYL AND AMINO-NITRILE CYANO-GUANIDINES | Société de Recherches et de Synthèses Organiques SA (CH) | 1982-08-11 | — | — | EP | disclosed |
| WO-1982000462-A1 | IMINO-ALKYL AND AMINO-NITRILE CYANO-GUANIDINES | RECH SYNTHESES ORGAN (CH) | 1982-02-18 | — | — | WO | disclosed |
| EP-0003640-B1 | ANTISECRETORY GUANIDINE DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-01-27 | — | — | EP | disclosed |
| EP-0041359-A1 | Process for the preparation of heterocyclylalkyl guanidines; intermediates and their preparation | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-12-09 | — | — | EP | disclosed |