SCHEMBL9630239

SCHEMBL9630239

CCN(c1[c]cccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.40
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
NR3C2 P08235 1/20 0.40
TSHR P16473 4/20 0.37
ALDH1A1 P00352 2/20 0.37
GLA P06280 1/20 0.37
HCN1 O60741 2/20 0.37
HCN4 Q9Y3Q4 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
KDM4C Q9H3R0 1/20 0.36
APAF1 O14727 1/20 0.36
CASP3 P42574 1/20 0.36
CASP6 P55212 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
EGFR P00533 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6417143 0.87 CYP2C19 (0.37) MAPTCRHBPCRHR2NPSR1NR3C2
SCHEMBL6612375 0.80 POLB (0.37) ALDH1A1L3MBTL1KDM4ETP53HSD17B10
Bromide SCHEMBL6737911 0.79 NR3C2 (0.55) MAPTCRHBPCRHR2NPSR1NR3C2
SCHEMBL4047345 0.78 ESR1 (0.36) MAPTTSHRCYP1A2KDM4ESMN1; SMN2
SCHEMBL9622532 0.77 ALDH1A1 (0.39) MAPTCRHBPCRHR2NPSR1TSHR
SCHEMBL128446 0.77 ALDH1A1 (0.39) MAPTCRHBPCRHR2NPSR1TSHR
SCHEMBL409370 0.76 NR3C2 (0.57) MAPTCRHBPCRHR2NPSR1NR3C2
SCHEMBL6567347 0.76 NR3C2 (0.57) MAPTCRHBPCRHR2NPSR1NR3C2
SCHEMBL350461 0.75 TSHR (0.38) MAPTTSHRALDH1A1CYP1A2CYP2D6
SCHEMBL28986655 0.75 FGFR1 (0.34) ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5124218-A Photoconductor element for making multiple copies and process for using same EASTMAN KODAK COMPANY (US) 1992-06-23 US disclosed
US-5053304-A Photoconductor element for making multiple copies and process for using same EASTMAN KODAK COMPANY (US) 1991-10-01 US disclosed
US-4452943-A ADDING NITRILE-CONTAINING MATERIAL TO NON-POLAR THERMOPLASTIC POLYMER GOLDMAN CONRAD 1984-06-05 US disclosed
US-4197120-A ELECTRICALLY PHOTOSENSITIVE PARTICLES CONTAINING COLORANT HAVING ABSORPTION MAXIMUM GREATER THAN 410 NANOMETERS EASTMAN KODAK COMPANY (US) 1980-04-08 US disclosed
US-RE30235-E FOR ELECTROPHORETIC MIGRATION IMAGING PROCESSES EASTMAN KODAK COMPANY (US) 1980-03-18 US disclosed
US-4175961-A DISPERSION OF A POLYMER HAVING ALKYLIDENE DIARYLENE GROUPS, A PYRYLIUM-TYPE DYE SALT, AND A BIS(N,N-DISUBSTITUTED ANILINE DERIVATIVE AS A SENSITIZER EASTMAN KODAK COMPANY (US) 1979-11-27 US disclosed
US-4127412-A BIS(AMINOARYL)ALKANES EASTMAN KODAK COMPANY (US) 1978-11-28 US disclosed
US-4111693-A PYRYLIUM TYPE DYE SALT EASTMAN KODAK COMPANY (US) 1978-09-05 US disclosed
US-4025341-A CONDENSATION POLYMER OF A TERTIARY AROMATIC AMINE, A SENSITIZER, AND A CARBONYL COMPOUND EASTMAN KODAK COMPANY (US) 1977-05-24 US disclosed
US-4012376-A Photosensitive colorant materials EASTMAN KODAK COMPANY (US) 1977-03-15 US disclosed