Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722446 | 0.88 | TSHR (0.33) | TSHRALDH1A1CYP3A4CNR2KMT2A | |
| SCHEMBL6553728 | 0.88 | ALDH1A1 (0.36) | TSHRALDH1A1CYP3A4CNR2KMT2A | |
| SCHEMBL5554891 | 0.85 | TSHR (0.56) | TSHRALDH1A1CNR2KMT2AL3MBTL1 | |
| SCHEMBL2456294 | 0.85 | MAPT (0.36) | TSHRALDH1A1KMT2AMEN1GAA | |
| SCHEMBL11794267 | 0.83 | PYCR1 (0.36) | TSHRALDH1A1CYP3A4MAPK1LMNA | |
| SCHEMBL6555084 | 0.83 | MAOB (0.33) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL816702 | 0.83 | TP53 (0.34) | — | |
| SCHEMBL2459640 | 0.82 | KCNH2 (0.41) | ALDH1A1CNR2RAB9ACYP1A2CYP2D6 | |
| SCHEMBL700216 | 0.80 | — | — | |
| SCHEMBL2460591 | 0.79 | TDP1 (0.37) | ALDH1A1CNR2KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2431 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3845535-B1 | HYDRAZINOPURINE COMPOUND AND TRIAZOLOPURINE COMPOUND FOR INHIBITING XANTHINE OXIDASE | TERA STONE CO LTD (JP) | 2024-06-26 | — | — | EP | claimed |
| CN-117624035-A | Pyridine salt singlet oxygen type active oxygen photosensitizer and preparation method and application thereof | 香港中文大学（深圳） | 2024-03-01 | — | — | CN | claimed |
| CN-117510474-A | Photochemical reaction long afterglow luminous photosensitizer material, nanoparticle, preparation method and application thereof | 华南理工大学 | 2024-02-06 | — | — | CN | claimed |
| WO-2024009215-A1 | NOVEL COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | DONG-A ST CO., LTD. (KR) | 2024-01-11 | — | — | WO | claimed |
| CN-113912483-A | Squaric acid derivative, maleic anhydride derivative, maleimide biological coupling material, preparation method and application thereof | 华南理工大学 | 2022-01-11 | — | — | CN | claimed |
| CN-111689955-A | Naphthothiadiazole free radical type photosensitizer and preparation method and application thereof | 华南理工大学 | 2020-09-22 | — | — | CN | claimed |
| EP-3143060-B1 | CATALYSTS FOR THE SYNTHESIS OF OXAZOLIDINONE COMPOUNDS | COVESTRO DEUTSCHLAND AG (DE) | 2020-06-24 | — | — | EP | claimed |
| CN-109880104-A | A kind of preparation method of phosphorus system organic silicon type fire retardant | 普信氟硅新材料（衢州）有限公司 | 2019-06-14 | — | — | CN | claimed |
| US-10294246-B2 | Substituted boronic acids and boronate esters as immunoproteasome inhibitors | MERCK PATENT GMBH (DE) | 2019-05-21 | — | — | US | claimed |
| CN-109651578-A | A kind of fire-retardant organic and inorganic resin of resistance to ablation and its preparation | 中昊北方涂料工业研究设计院有限公司 | 2019-04-19 | — | — | CN | claimed |
| US-4567124-A | STIBENE COMPOUND | RICOH CO., LTD. (JP) | 1986-01-28 | — | — | US | claimed |
| US-4552825-A | Phosphorous diketonate electron accepting ring compounds as sensitizers for electron donating photoconductive compositions | EASTMAN KODAK COMPANY (US) | 1985-11-12 | — | — | US | claimed |
| US-4496730-A | Phosphorous diketonate electron accepting ring compounds as sensitizers for electron donating photoconductive compositions | EASTMAN KODAK COMPANY (US) | 1985-01-29 | — | — | US | claimed |
| US-4454211-A | Electrophotographic photosensitive member with pyrazoline charge transport material | CANON KABUSHIKI KAISHA (JP) | 1984-06-12 | — | — | US | claimed |
| US-4394428-A | IMPROVED QUANTUM EFFICIENCY | EASTMAN KODAK COMPANY (US) | 1983-07-19 | — | — | US | claimed |
| EP-0076088-A2 | A photoconductive composition and a photoconductive element comprising the composition | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1983-04-06 | — | — | EP | claimed |
| US-4332809-A | ANTIALLERGENS | TANABE SEIYAKU CO., LTD. (JP) | 1982-06-01 | — | — | US | claimed |
| US-4214093-A | PROTEOLYTIC ENZYME INHIBITORS | TORII & CO., LTD. (JP) | 1980-07-22 | — | — | US | claimed |
| US-4145215-A | PHOTOCONDUCTIVE PIGMENTS | EASTMAN KODAK COMPANY (US) | 1979-03-20 | — | — | US | claimed |
| US-3966703-A | Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | claimed |