Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9181823 | 0.87 | CYP3A4 (0.40) | CYP3A4 | |
| SCHEMBL11765634 | 0.85 | CYP3A4 (0.40) | CYP3A4 | |
| SCHEMBL1035105 | 0.85 | CYP3A4 (0.40) | CYP3A4GABRA1GABRB2 | |
| SCHEMBL28683617 | 0.84 | CYP3A4 (0.39) | CYP3A4GABRA1GABRB2 | |
| SCHEMBL2298259 | 0.82 | CYP3A4 (0.41) | CYP3A4GABRA1GABRB2 | |
| SCHEMBL5961207 | 0.80 | KCNN4 (0.31) | — | |
| SCHEMBL10959516 | 0.79 | GABRA1 (0.40) | CYP3A4GABRA1GABRB2 | |
| SCHEMBL14656230 | 0.78 | CYP3A4 (0.65) | CYP3A4GABRA1GABRB2 | |
| SCHEMBL2476985 | 0.76 | KCNN4 (0.35) | CYP3A4GABRA1GABRB2 | |
| SCHEMBL11881605 | 0.75 | CYP1A2 (0.31) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301302-B1 | PROCESS FOR THE PREPARATION OF POLYURETHANE FOAMS | Th. Goldschmidt AG (DE) | 1992-11-19 | — | — | EP | disclosed |
| EP-0301307-B1 | PROCESS FOR THE PREPARATION OF POLYURETHANE FOAMS | Th. Goldschmidt AG (DE) | 1992-04-15 | — | — | EP | disclosed |
| US-4837244-A | FOAM STABILIZER IS POLYOXYALKYLENE ETHER OF ALKYLPHENOL-ALDEHYDE | TH. GOLDSCHMIDT AG (DE) | 1989-06-06 | — | — | US | disclosed |
| EP-0301307-A2 | Process for the preparation of polyurethane foams | Th. Goldschmidt AG (DE) | 1989-02-01 | — | — | EP | disclosed |
| EP-0301302-A2 | Process for the preparation of polyurethane foams | Th. Goldschmidt AG (DE) | 1989-02-01 | — | — | EP | disclosed |
| EP-0045090-B1 | URETHANE CATALYSIS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1985-12-04 | — | — | EP | disclosed |
| EP-0134338-A1 | Process for preparing polyol-catalyst mixtures useful in the preparation of rigid polyurethane cellular products | TEXACO DEVELOPMENT CORPORATION (US) | 1985-03-20 | — | — | EP | disclosed |
| US-4465791-A | REACTING WATER, A MANNICH BASE COMPOUND AND AN EPOXIDE | TEXACO INC. (PARENT) (US) | 1984-08-14 | — | — | US | disclosed |
| US-4404120-A | REACTION OF AN OXIRANE COMPOUND WITH AN AMINE IN THE PRESENCE OF AN ALDEHYDE | TEXACO INC. (US) | 1983-09-13 | — | — | US | disclosed |
| US-4404121-A | REACTING A MANNICH BASE WITH WATER AND AN EPOXIDE | TEXACO INC. (US) | 1983-09-13 | — | — | US | disclosed |
| US-4286073-A | Urethane catalysis | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1981-08-25 | — | — | US | disclosed |
| US-4116879-A | Quaternary hydroxyalkyl tertiary amine bases as polyurethane catalysts | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1978-09-26 | — | — | US | disclosed |
| US-3988267-A | Quaternary hydroxyalkyl tertiary amine bases as polyurethane catalysts | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1976-10-26 | — | — | US | disclosed |