Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957255 | 0.86 | MAOB (0.52) | MAOBRAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL7957251 | 0.86 | MAOB (0.49) | MAOBRAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL28256912 | 0.86 | MAOB (0.65) | MAOBRAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL9748049 | 0.86 | MAOB (0.74) | MAOBRAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL10750881 | 0.86 | MAOB (0.74) | MAOBSMN1; SMN2MAPTMAOA | |
| Hydrochloric Acid SCHEMBL9440732 | 0.84 | MAOB (0.58) | MAOBSMN1; SMN2ALDH1A1HPGDNR4A2 | |
| SCHEMBL24379272 | 0.83 | MAOB (0.58) | MAOBRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL28065631 | 0.83 | ALDH1A1 (0.62) | MAOBRAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL27731757 | 0.83 | MAOB (0.58) | MAOBRAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL9440720 | 0.83 | MAOB (0.57) | MAOBRAB9ASMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109195608-A | Boron-containing small molecules | 比尔及梅琳达盖茨基金会 | 2019-01-11 | — | — | CN | disclosed |
| CN-102670617-B | Application of ibuprofen 2-(2-arylmorpholine-4-yl) ethyl ester in preparation of antidepressant drugs | UNIV HUNAN | 2013-03-20 | — | — | CN | disclosed |
| CN-102670617-A | Application of ibuprofen 2-(2-arylmorpholine-4-yl) ethyl ester in preparation of antidepressant drugs | UNIV HUNAN | 2012-09-19 | — | — | CN | disclosed |
| CN-101357901-B | Chiral 1,4-dihydro-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic carboxylate, preparation method and application thereof | UNIV HUNAN | 2011-06-08 | — | — | CN | disclosed |
| CN-101357901-A | Chiral 1,4-dihydro-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic carboxylate, preparation method and application thereof | UNIV HUNAN (CN) | 2009-02-04 | — | — | CN | disclosed |
| CN-100339371-C | Novel aryloxy-alkyl-dialkylamines compound | AMERICAN HOME PROD (US) | 2007-09-26 | — | — | CN | disclosed |
| CN-1765891-A | Novel aryloxy-alkyl-dialkylamines compound | AMERICAN HOME PROD (US) | 2006-05-03 | — | — | CN | disclosed |
| CN-1231458-C | Novel aryloxy-alkyl-dialkylamines | WYETH CORP (US) | 2005-12-14 | — | — | CN | disclosed |
| CN-1281429-A | Novel aryloxy-alkyl-dialkylamines | AMERICAN HOME PROD (US) | 2001-01-24 | — | — | CN | disclosed |
| US-5096929-A | Inotropic agents; vasodilation | CHIESI FARMACEUTICI S.P.A. (IT) | 1992-03-17 | — | — | US | disclosed |