Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.56 |
| ▸ | NQO2 | P16083 | 16/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 16/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629876 | 0.87 | MTNR1A (0.58) | MTNR1ANQO2MTNR1B | |
| SCHEMBL6976751 | 0.82 | HTR2C (0.38) | MTNR1ANQO2MTNR1B | |
| SCHEMBL7220825 | 0.82 | HTR2C (0.44) | MTNR1ANQO2MTNR1BPDE4APDE4B | |
| SCHEMBL6968070 | 0.80 | PPARD (0.41) | MTNR1ANQO2MTNR1B | |
| SCHEMBL6978852 | 0.79 | CA2 (0.45) | MTNR1AMTNR1BPDE4APDE4BPDE4C | |
| SCHEMBL14143008 | 0.79 | CA2 (0.45) | MTNR1AMTNR1BPDE4APDE4BPDE4C | |
| SCHEMBL11647146 | 0.78 | MTNR1A (0.62) | MTNR1ANQO2MTNR1B | |
| SCHEMBL7214795 | 0.78 | GRIN2B (0.41) | — | |
| SCHEMBL23343762 | 0.77 | MTNR1A (0.64) | MTNR1ANQO2MTNR1B | |
| SCHEMBL9630431 | 0.77 | MTNR1A (0.60) | MTNR1ANQO2MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213080-B1 | HYDROGENATED PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-05-20 | — | — | EP | disclosed |
| EP-0213080-A2 | Hydrogenated pyridine derivatives | CIBA-GEIGY AG (CH) | 1987-03-04 | — | — | EP | disclosed |