Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14078043 | 0.93 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAL3MBTL1GAASLC6A2 | |
| SCHEMBL14387788 | 0.90 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAL3MBTL1GAASLC6A2 | |
| SCHEMBL28994745 | 0.88 | LMNA (0.47) | SMN1; SMN2LMNAL3MBTL1GAASLC6A2 | |
| SCHEMBL20779411 | 0.82 | L3MBTL1 (0.43) | SMN1; SMN2LMNAL3MBTL1GAASLC6A2 | |
| SCHEMBL9830214 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAL3MBTL1GAASLC6A2 | |
| SCHEMBL906187 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAL3MBTL1GAASLC6A2 | |
| SCHEMBL7914382 | 0.79 | AOC3 (0.58) | LMNASLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL15675981 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAL3MBTL1GAASLC6A2 | |
| SCHEMBL18947499 | 0.76 | CFTR (0.46) | SMN1; SMN2LMNAL3MBTL1GAASLC6A2 | |
| SCHEMBL1579049 | 0.75 | LMNA (0.57) | SMN1; SMN2LMNAL3MBTL1GAASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316783-B1 | PROCESS FOR THE PREPARATION OF HETERO-AROMATIC KETONES AND ALDEHYDES | BASF Aktiengesellschaft (DE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0356843-A2 | Process for the preparation of heteroaromatic aldehydes and ketones | BASF Aktiengesellschaft (DE) | 1990-03-07 | — | — | EP | disclosed |
| EP-0316783-A1 | Process for the preparation of hetero-aromatic ketones and aldehydes | BASF Aktiengesellschaft (DE) | 1989-05-24 | — | — | EP | disclosed |