Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | EZH2 | Q15910 | 11/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10112879 | 0.82 | ESR1 (0.45) | POLBGAAESR1ESR2EZH2 | |
| SCHEMBL8993553 | 0.81 | ESR1 (0.52) | GAAESR1ESR2CYP3A4 | |
| SCHEMBL9846995 | 0.80 | ESR1 (0.50) | ESR1ESR2KCNH2CYP3A4SLC6A4 | |
| SCHEMBL9846972 | 0.78 | ESR1 (0.51) | POLBGAAESR1ESR2KCNH2 | |
| SCHEMBL17042465 | 0.77 | ESR1 (0.59) | ESR1ESR2CYP3A4 | |
| SCHEMBL9846977 | 0.74 | POLB (0.56) | POLBGAAESR1ESR2EZH2 | |
| SCHEMBL10000525 | 0.73 | ESR1 (0.66) | GAAESR1ESR2 | |
| SCHEMBL827205 | 0.73 | ESR1 (0.69) | ESR1ESR2CYP3A4 | |
| SCHEMBL9472412 | 0.71 | ESR1 (0.67) | ESR1ESR2CYP3A4 | |
| SCHEMBL3421693 | 0.71 | POLB (0.79) | POLBGAAEZH2KCNH2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5105004-A | For the preparation of heat stable plastics | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-14 | — | — | US | disclosed |
| EP-0413233-A2 | Copolyamides with higher glas transition temperature | BAYER AG (DE) | 1991-02-20 | — | — | EP | disclosed |
| EP-0379006-A2 | Aminoarylethers | BAYER AG (DE) | 1990-07-25 | — | — | EP | disclosed |
| EP-0363760-A1 | Aromatic ethers | BAYER AG (DE) | 1990-04-18 | — | — | EP | disclosed |