Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | EZH2 | Q15910 | 8/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630764 | 0.82 | POLB (0.50) | ESR1ESR2EZH2ARSLC6A4 | |
| SCHEMBL10112950 | 0.77 | TLR8 (0.49) | ESR1ESR2TLR8MAPTHSD11B1 | |
| SCHEMBL10112886 | 0.77 | TLR8 (0.49) | ESR1ESR2TLR8MAPTHSD11B1 | |
| SCHEMBL10112898 | 0.76 | TLR8 (0.46) | ESR1TLR8MAPTHSD11B1EZH2 | |
| SCHEMBL8993553 | 0.76 | ESR1 (0.52) | ESR1ESR2MAPTKDM4ECYP2D6 | |
| SCHEMBL9846995 | 0.74 | ESR1 (0.50) | ESR1ESR2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL17042465 | 0.73 | ESR1 (0.59) | ESR1ESR2CYP2D6 | |
| SCHEMBL10112892 | 0.72 | TLR8 (0.47) | TLR8MAPTHSD11B1EZH2BCL2L1 | |
| SCHEMBL9846972 | 0.72 | ESR1 (0.51) | ESR1ESR2MAPTKDM4ESLC6A2 | |
| SCHEMBL25986540 | 0.72 | ESR1 (0.60) | ESR1ESR2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120052412-A1 | POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF | HONDA MOTOR CO., LTD. (JP) | 2012-03-01 | — | — | US | disclosed |