Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 5/20 | 0.56 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.56 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.49 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 5/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619135 | 0.84 | SERPINA6 (0.62) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL7706598 | 0.83 | SERPINA6 (0.64) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL3816344 | 0.80 | SERPINA6 (0.72) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL1711186 | 0.79 | SERPINA6 (0.58) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL16188590 | 0.78 | SHBG (0.69) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL517355 | 0.78 | SHBG (0.69) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL7615553 | 0.78 | SHBG (0.69) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL16741266 | 0.78 | SHBG (0.69) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL16188696 | 0.78 | SHBG (0.69) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL1711107 | 0.78 | SHBG (0.68) | SHBGSERPINA6SLC22A1ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310645-B1 | COMPOUNDS USEFUL PARTICULARLY FOR RADIOTHERAPY OR IMAGING OF CANCER | IRE-CELLTARG S.A. (BE) | 1992-06-10 | — | — | EP | disclosed |
| EP-0310645-A1 | COMPOUNDS USEFUL PARTICULARLY FOR RADIOTHERAPY OR IMAGING OF CANCER. | IRECELLTARG S A (BE) | 1989-04-12 | — | — | EP | disclosed |
| WO-1988007986-A2 | COMPOUNDS USEFUL PARTICULARLY FOR RADIOTHERAPY OR IMAGING OF CANCER | IRE-CELLTARG S.A. (BE) | 1988-10-20 | — | — | WO | disclosed |