Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.78 |
| ▸ | DRD2 | P14416 | 8/20 | 0.77 |
| ▸ | DRD3 | P35462 | 8/20 | 0.77 |
| ▸ | HTR1A | P08908 | 7/20 | 0.77 |
| ▸ | HTR2A | P28223 | 6/20 | 0.77 |
| ▸ | HTR7 | P34969 | 5/20 | 0.77 |
| ▸ | DRD4 | P21917 | 4/20 | 0.77 |
| ▸ | DRD1 | P21728 | 4/20 | 0.77 |
| ▸ | DRD5 | P21918 | 3/20 | 0.77 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.77 |
| ▸ | HRH1 | P35367 | 2/20 | 0.77 |
| ▸ | HTR2C | P28335 | 2/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15961344 | 0.92 | POLB (0.92) | POLBDRD2DRD3HTR1AHTR2A | |
| SCHEMBL15961309 | 0.87 | POLB (1.00) | POLBDRD2DRD3HTR1AHTR2A | |
| SCHEMBL27237006 | 0.87 | HTR1A (1.00) | POLBDRD2DRD3HTR1AHTR2A | |
| SCHEMBL27236997 | 0.87 | DRD3 (1.00) | POLBDRD2DRD3HTR1AHTR2A | |
| SCHEMBL9632489 | 0.86 | POLB (0.72) | POLBDRD2DRD3HTR1AHTR2A | |
| SCHEMBL4519313 | 0.85 | KCNH2 (0.85) | POLBDRD2DRD3HTR1AHTR2A | |
| SCHEMBL26107525 | 0.85 | KCNH2 (0.85) | POLBDRD2DRD3HTR1AHTR2A | |
| SCHEMBL26108725 | 0.85 | KCNH2 (0.85) | POLBDRD2DRD3HTR1AHTR2A | |
| SCHEMBL9633099 | 0.85 | HTR1A (0.75) | POLBDRD2DRD3HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL26108256 | 0.84 | KCNH2 (0.83) | POLBDRD2DRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089497-A | Dopaminergic agents | WARNER-LAMBERT COMPANY (US) | 1992-02-18 | — | — | US | claimed |
| US-5089497-A | Dopaminergic agents | WARNER-LAMBERT COMPANY (US) | 1992-02-18 | — | — | US | disclosed |