Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.75 |
| ▸ | DRD2 | P14416 | 7/20 | 0.75 |
| ▸ | DRD3 | P35462 | 7/20 | 0.75 |
| ▸ | HTR2A | P28223 | 5/20 | 0.75 |
| ▸ | DRD1 | P21728 | 3/20 | 0.75 |
| ▸ | DRD5 | P21918 | 2/20 | 0.75 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.59 |
| ▸ | DRD4 | P21917 | 5/20 | 0.55 |
| ▸ | HTR7 | P34969 | 4/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.55 |
| ▸ | HRH1 | P35367 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631368 | 0.85 | POLB (0.78) | HTR1ADRD2DRD3HTR2ADRD1 | |
| SCHEMBL26108581 | 0.82 | HTR1A (0.65) | HTR1ADRD2DRD3HTR2ADRD1 | |
| SCHEMBL26492991 | 0.82 | HTR1A (0.65) | HTR1ADRD2DRD3HTR2ADRD1 | |
| Hydrochloric Acid SCHEMBL26108377 | 0.81 | DRD2 (0.63) | HTR1ADRD2DRD3HTR2ADRD1 | |
| SCHEMBL9260064 | 0.78 | HTR1A (0.60) | HTR1ADRD2DRD3HTR2ADRD1 | |
| SCHEMBL7787481 | 0.78 | HTR2A (0.72) | HTR1ADRD2DRD3HTR2ADRD1 | |
| SCHEMBL388434 | 0.77 | DRD2 (0.47) | HTR1ADRD2DRD3HTR2ADRD1 | |
| SCHEMBL9631663 | 0.77 | HTR1A (0.61) | HTR1ADRD2DRD3HTR2ADRD1 | |
| SCHEMBL5430295 | 0.77 | ADRA1A (0.72) | HTR1ADRD2DRD3HTR2ADRD1 | |
| Hydrochloric Acid SCHEMBL10423847 | 0.77 | HTR1A (0.64) | HTR1ADRD2DRD3HTR2ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089497-A | Dopaminergic agents | WARNER-LAMBERT COMPANY (US) | 1992-02-18 | — | — | US | claimed |
| US-5089497-A | Dopaminergic agents | WARNER-LAMBERT COMPANY (US) | 1992-02-18 | — | — | US | disclosed |