Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2607204 | 0.93 | NCF1 (0.41) | POLBKMT2APARP14ALDH1A1L3MBTL1 | |
| SCHEMBL2607044 | 0.89 | SMN1; SMN2 (0.45) | SMN1; SMN2POLBTDP1KMT2AALDH1A1 | |
| SCHEMBL12617901 | 0.87 | KMT2A (0.41) | POLBTDP1KMT2APARP14ALDH1A1 | |
| SCHEMBL15800376 | 0.85 | POLB (0.40) | SMN1; SMN2POLBKMT2APARP14ALDH1A1 | |
| SCHEMBL12881605 | 0.84 | CHRM1 (0.47) | SMN1; SMN2POLBTDP1PARP14ALDH1A1 | |
| SCHEMBL1881523 | 0.82 | ALDH1A1 (0.46) | POLBTDP1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL1439129 | 0.82 | TDP1 (0.48) | POLBTDP1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL25311355 | 0.81 | TDP1 (0.50) | POLBTDP1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL18797 | 0.81 | TDP1 (0.50) | POLBTDP1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL2779505 | 0.81 | TDP1 (0.50) | POLBTDP1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079249-A | Serotine antagonists at 5-HT2 level, antiallergens, antihistamines | ADIR ET COMPAGNIE (FR) | 1992-01-07 | — | — | US | disclosed |
| US-5071847-A | BIS (ARYL) ALKENE COMPOUNDS OF HOMOPIPERIDINES USEFUL AS SEROTONIN-ANTAGONISTS | ADIR ET COMPAGNIE (FR) | 1991-12-10 | — | — | US | disclosed |
| US-5028607-A | Antiserotonine agents | ADIR ET COMPAGNIE (FR) | 1991-07-02 | — | — | US | disclosed |