Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 7/20 | 0.44 |
| ▸ | CES2 | O00748 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130944 | 0.78 | CES1 (0.41) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL4188899 | 0.76 | CES1 (0.48) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL8724219 | 0.76 | CES1 (0.48) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL4188137 | 0.76 | TSHR (0.55) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL23706122 | 0.75 | TDP1 (0.42) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL23706124 | 0.75 | TDP1 (0.42) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL11056391 | 0.74 | CES2 (0.59) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL28653461 | 0.74 | CES1 (0.46) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL11056387 | 0.74 | CES2 (0.59) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL2234110 | 0.74 | CES1 (0.47) | CES1CES2ALDH1A1TSHRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269821-B1 | OPTICAL WAVEGUIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-04-01 | — | — | EP | disclosed |
| EP-0269821-A1 | Optical waveguide | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-08 | — | — | EP | disclosed |
| EP-0267460-A1 | Transparent polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-18 | — | — | EP | disclosed |