Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.48 |
| ▸ | CES2 | O00748 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724219 | 1.00 | CES1 (0.48) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL8392056 | 0.80 | CES1 (0.48) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL25249496 | 0.79 | ALOX15 (0.54) | CES1CES2TSHRALDH1A1CA2 | |
| SCHEMBL30873595 | 0.79 | ALOX15 (0.54) | CES1CES2TSHRALDH1A1CA2 | |
| SCHEMBL28653461 | 0.78 | CES1 (0.46) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL2234110 | 0.78 | CES1 (0.47) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL3929950 | 0.78 | CES1 (0.47) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL18985177 | 0.78 | CES1 (0.47) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL9631465 | 0.76 | CES1 (0.44) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL17847697 | 0.76 | CES1 (0.48) | CES1CES2TSHRALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021119554-A1 | COMPOSITIONS AND METHODS FOR POTENTIATING IMMUNE ACTIVITY | KUMQUAT BIOSCIENCES INC. (US) | 2021-06-17 | — | — | WO | disclosed |
| WO-2020252075-A1 | LIGAND-EXCHANGEABLE JANUS NANOPARTICLES AND METHODS OF MAKING THE SAME | ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) | 2020-12-17 | — | — | WO | disclosed |
| US-20090092975-A1 | SELECTABLE MARKER | MOLOGIC LTD (GB) | 2009-04-09 | — | — | US | disclosed |
| US-20080200731-A1 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2008-08-21 | — | — | US | disclosed |
| US-7381832-B2 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2008-06-03 | — | — | US | disclosed |
| EP-1735262-A1 | PROCESS FOR PREPARING CINNAMIC ACIDS AND ALKYL ESTERS THEREOF | Honeywell International, Inc. (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005105728-A1 | PROCESS FOR PREPARING CINNAMIC ACIDS AND ALKYL ESTERS THEREOF | HONEYWELL INTERNATIONAL INC. (US) | 2005-11-10 | — | — | WO | disclosed |
| US-20050234264-A1 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-10-20 | — | — | US | disclosed |
| US-20050234261-A1 | Process for preparing cinnamic acids and alkyl esters thereof | HONEYWELL INTERNATIONAL INC. | 2005-10-20 | — | — | US | disclosed |
| US-6956129-B2 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-10-18 | — | — | US | disclosed |
| EP-1360489-A1 | LOW AFFINITY SCREENING METHOD | Graffinity Pharmaceuticals Aktiengesellschaft (DE) | 2003-11-12 | — | — | EP | disclosed |
| US-20020115885-A1 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2002-08-22 | — | — | US | disclosed |
| WO-2002063299-A1 | LOW AFFINITY SCREENING METHOD | GRAFFINITY PHARMACEUTICALS AG (DE) | 2002-08-15 | — | — | WO | disclosed |
| US-5744273-A | Laminatable backing substrates containing fluoro compounds for improved toner flow | XEROX CORPORATION (US) | 1998-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090092975-A1 | SELECTABLE MARKER | AMD1, PADI1, PSAT1 | CES1 75/4885CES2 849/4885TSHR 3826/4885 |
| US-20050234264-A1 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | DDT, DDC, NISCH | CES1 560/4885CES2 161/4885TSHR 4347/4885 |
| US-20080200731-A1 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | DDT, DDC, NISCH | CES1 560/4885CES2 161/4885TSHR 4347/4885 |
| US-20020115885-A1 | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives | DDT, DDC, NISCH | CES1 573/4885CES2 165/4885TSHR 4435/4885 |
| US-20050234261-A1 | Process for preparing cinnamic acids and alkyl esters thereof | PCCA, LIPA, CA7 | CES1 40/4885CES2 8/4885TSHR 1266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.