Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.34 |
| ▸ | FDPS | P14324 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632030 | 1.00 | ALOX15 (0.59) | ALOX15ALDH1A1USP2TDP1TSHR | |
| SCHEMBL9632911 | 0.87 | ALOX15 (0.68) | ALOX15ALDH1A1USP2TDP1TSHR | |
| SCHEMBL9632904 | 0.87 | ALOX15 (0.68) | ALOX15ALDH1A1USP2TDP1TSHR | |
| SCHEMBL29216408 | 0.82 | ALOX15 (0.67) | ALOX15ALDH1A1USP2TDP1TSHR | |
| SCHEMBL3125002 | 0.82 | ALOX15 (0.61) | ALOX15ALDH1A1USP2TDP1TSHR | |
| SCHEMBL3108399 | 0.82 | ALOX15 (0.61) | ALOX15ALDH1A1USP2TDP1TSHR | |
| SCHEMBL3108390 | 0.82 | ALOX15 (0.61) | ALOX15ALDH1A1USP2TDP1TSHR | |
| SCHEMBL9632588 | 0.82 | ALOX15 (0.73) | ALOX15ALDH1A1USP2TDP1TSHR | |
| SCHEMBL9632581 | 0.82 | ALOX15 (0.73) | ALOX15ALDH1A1USP2TDP1TSHR | |
| SCHEMBL11041920 | 0.80 | ALOX15 (0.59) | ALOX15ALDH1A1USP2TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513761-A2 | Bisphosphonate squalene synthetase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1992-11-19 | — | — | EP | disclosed |
| US-5157027-A | Anticholesterol agents | E. R. SQUIBB & SONS, INC. (US) | 1992-10-20 | — | — | US | disclosed |