Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.37 |
| ▸ | FDPS | P14324 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632911 | 1.00 | ALOX15 (0.68) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL9632030 | 0.87 | ALOX15 (0.59) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL9632041 | 0.87 | ALOX15 (0.59) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL8256070 | 0.86 | ALOX15 (0.61) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL8652505 | 0.84 | ALOX15 (0.65) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL538858 | 0.84 | ALOX15 (0.65) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL3117924 | 0.81 | ALOX15 (0.68) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL10520930 | 0.81 | ALOX15 (0.68) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL1200047 | 0.81 | ALOX15 (0.68) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL10520940 | 0.81 | ALOX15 (0.68) | ALOX15ALDH1A1TSHRUSP2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402461-B | Method for preparing guaiazupyridine type sesquiterpene alkaloid | 中国科学院新疆理化技术研究所 | 2023-02-03 | — | — | CN | claimed |
| CN-113402461-A | Method for preparing guaiazupyridine type sesquiterpene alkaloid | 中国科学院新疆理化技术研究所 | 2021-09-17 | — | — | CN | claimed |
| CN-113402461-B | Method for preparing guaiazupyridine type sesquiterpene alkaloid | 中国科学院新疆理化技术研究所 | 2023-02-03 | — | — | CN | disclosed |
| CN-113402461-A | Method for preparing guaiazupyridine type sesquiterpene alkaloid | 中国科学院新疆理化技术研究所 | 2021-09-17 | — | — | CN | disclosed |
| EP-0513761-A2 | Bisphosphonate squalene synthetase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1992-11-19 | — | — | EP | disclosed |
| US-5157027-A | Anticholesterol agents | E. R. SQUIBB & SONS, INC. (US) | 1992-10-20 | — | — | US | disclosed |