SCHEMBL9632059

SCHEMBL9632059

C[Si](C)(c1ccccc1)C1c2ccccc2-c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.40
POLB P06746 2/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
ATM Q13315 1/20 0.36
HTR2A P28223 1/20 0.35
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
ALDH1A1 P00352 1/20 0.34
ACHE P22303 2/20 0.33
CHRM2 P08172 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD1 P21728 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
ADRA1A P35348 1/20 0.33
OPRM1 P35372 1/20 0.33
DRD3 P35462 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9632808 0.83 POLB (0.40) GPR3POLBKMT2AMEN1ATM
Hydrochloric Acid SCHEMBL10321197 0.82 GPR3 (0.32) GPR3
SCHEMBL5980986 0.79 GPR3 (0.39) GPR3POLBKMT2AMEN1ATM
SCHEMBL8970979 0.79 GPR3 (0.38) GPR3POLBKMT2AMEN1ATM
Hydrochloric Acid SCHEMBL10317528 0.79 ESR1 (0.31) ESR1ESR2
SCHEMBL10321198 0.78
SCHEMBL19180887 0.77 GPR3 (0.38) GPR3POLBKMT2AMEN1ATM
SCHEMBL9631640 0.77 GPR3 (0.38) GPR3POLBKMT2AMEN1ATM
SCHEMBL29901616 0.77 GPR3 (0.38) GPR3POLBKMT2AMEN1ATM
SCHEMBL5175634 0.77 GPR3 (0.46) GPR3POLBKMT2AMEN1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5101059-A Xanthene compounds RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1992-03-31 US disclosed
WO-1991008190-A1 AMINO ACID PROTECTING GROUPS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-06-13 WO disclosed