Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GPR3 | P46089 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632059 | 0.83 | GPR3 (0.40) | POLBGPR3KMT2AMEN1ATM | |
| Hydrochloric Acid SCHEMBL10320324 | 0.82 | MEN1 (0.33) | POLBGPR3KMT2AMEN1ATM | |
| SCHEMBL5980986 | 0.79 | GPR3 (0.39) | POLBGPR3KMT2AMEN1ATM | |
| SCHEMBL8970979 | 0.79 | GPR3 (0.38) | POLBGPR3KMT2AMEN1ATM | |
| SCHEMBL9631640 | 0.77 | GPR3 (0.38) | POLBGPR3KMT2AMEN1ATM | |
| SCHEMBL29901616 | 0.77 | GPR3 (0.38) | POLBGPR3KMT2AMEN1ATM | |
| SCHEMBL19180887 | 0.77 | GPR3 (0.38) | POLBGPR3KMT2AMEN1ATM | |
| SCHEMBL6671925 | 0.77 | GPR3 (0.46) | POLBGPR3KMT2AMEN1ATM | |
| SCHEMBL30390148 | 0.77 | GPR3 (0.46) | POLBGPR3KMT2AMEN1ATM | |
| SCHEMBL5175634 | 0.77 | GPR3 (0.46) | POLBGPR3KMT2AMEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5101059-A | Xanthene compounds | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-03-31 | — | — | US | disclosed |
| WO-1991008190-A1 | AMINO ACID PROTECTING GROUPS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-06-13 | — | — | WO | disclosed |