Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 9/20 | 0.32 |
| ▸ | MPC2 | O95563 | 2/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631974 | 0.94 | CYP3A4 (0.44) | CYP3A4ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL10639871 | 0.93 | CYP3A4 (0.39) | CYP3A4ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL10636537 | 0.84 | CYP3A4 (0.42) | CYP3A4ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL9630752 | 0.83 | CYP3A4 (0.48) | CYP3A4ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL9630958 | 0.82 | KDM4E (0.37) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL9632033 | 0.81 | CYP3A4 (0.46) | CYP3A4ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL10642008 | 0.81 | ALDH1A1 (0.44) | CYP3A4ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL10641821 | 0.81 | KMT2A (0.45) | CYP3A4ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL9632121 | 0.80 | ALDH1A1 (0.41) | CYP3A4ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL9630834 | 0.78 | KDM4E (0.37) | ALDH1A1HPGDHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |