Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632290 | 0.92 | ALDH1A1 (0.44) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL9630958 | 0.89 | KDM4E (0.37) | ALDH1A1NPC1KDM4ESMN1; SMN2GAA | |
| SCHEMBL9532298 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL9632256 | 0.83 | TLR3 (0.46) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL9631974 | 0.82 | CYP3A4 (0.44) | ALDH1A1MAPTHPGDHSD17B10KMT2A | |
| SCHEMBL9630834 | 0.82 | KDM4E (0.37) | ALDH1A1KDM4ESMN1; SMN2GAAHPGD | |
| SCHEMBL9633233 | 0.81 | RECQL (0.37) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL9631291 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL10640498 | 0.80 | KDM4E (0.39) | ALDH1A1NPC1KDM4ESMN1; SMN2GAA | |
| SCHEMBL9632087 | 0.80 | CYP3A4 (0.37) | ALDH1A1MAPTKDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |