Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
| ▸ | ACP3 | P15309 | 3/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MMP14 | P50281 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632106 | 1.00 | FDPS (0.39) | FDPSACP3MMP8MMP14CA14 | |
| SCHEMBL9633235 | 0.79 | GRIK1 (0.52) | FDPSACP3MMP8MMP14CA14 | |
| SCHEMBL9632094 | 0.79 | GRIK1 (0.52) | FDPSACP3MMP8MMP14CA14 | |
| SCHEMBL9632086 | 0.79 | GRIK1 (0.52) | FDPSACP3MMP8MMP14CA14 | |
| SCHEMBL9632541 | 0.78 | FDPS (0.43) | FDPSACP3MMP8MMP14CA14 | |
| SCHEMBL9632549 | 0.78 | FDPS (0.43) | FDPSACP3MMP8MMP14CA14 | |
| SCHEMBL9632013 | 0.76 | BACE1 (0.42) | FDPSACP3 | |
| SCHEMBL9631999 | 0.76 | BACE1 (0.42) | FDPSACP3 | |
| SCHEMBL6546663 | 0.73 | TLR8 (0.46) | PPARGPPARASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9634077 | 0.72 | HDAC3 (0.40) | FDPSCA2CA9PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513761-A2 | Bisphosphonate squalene synthetase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1992-11-19 | — | — | EP | claimed |
| EP-0513761-A2 | Bisphosphonate squalene synthetase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1992-11-19 | — | — | EP | disclosed |
| US-5157027-A | Anticholesterol agents | E. R. SQUIBB & SONS, INC. (US) | 1992-10-20 | — | — | US | disclosed |